Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 14/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19710933 | 1.00 | PIK3CD (1.00) | PIK3CDKDM4EPKMALDH1A1KMT2A | |
| SCHEMBL19710930 | 0.82 | PIK3CD (0.70) | PIK3CDKDM4EPKMALDH1A1KMT2A | |
| SCHEMBL22055736 | 0.79 | PIK3CD (0.65) | PIK3CDKDM4EPKMALDH1A1KMT2A | |
| SCHEMBL19701902 | 0.77 | PIK3CD (1.00) | PIK3CD | |
| SCHEMBL19701907 | 0.74 | PIK3CD (1.00) | PIK3CD | |
| SCHEMBL19711140 | 0.73 | PIK3CD (1.00) | PIK3CD | |
| SCHEMBL19701896 | 0.73 | PIK3CD (1.00) | PIK3CD | |
| SCHEMBL19701904 | 0.73 | PIK3CD (1.00) | PIK3CDALDH1A1KMT2A | |
| SCHEMBL19701900 | 0.72 | PIK3CD (1.00) | PIK3CD | |
| SCHEMBL19710932 | 0.72 | PIK3CD (1.00) | PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170355707-A1 | BICYCLIC HETEROARYL AMINE COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2017-12-14 | — | — | US | disclosed |
| US-20170355707-A1 | BICYCLIC HETEROARYL AMINE COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2017-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170355707-A1 | BICYCLIC HETEROARYL AMINE COMPOUNDS | PIK3R3, JAK2, JAK3 | PIK3CD 14/4885KDM4E 2233/4885PKM 2814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.