SCHEMBL19702995

SCHEMBL19702995

C/C=C/C1CCC(c2ccc(-c3ccc(-c4ccc(C)cc4)c(F)c3)cc2)CC1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.40
CYP2C9 P11712 2/20 0.40
APP P05067 2/20 0.40
CYP2D6 P10635 1/20 0.38
CYP2C19 P33261 1/20 0.38
PDE3B Q13370 1/20 0.36
PDE3A Q14432 1/20 0.36
SLC18A3 Q16572 1/20 0.32
PTGS2 P35354 2/20 0.31
FASN P49327 1/20 0.31
LRRK2 Q5S007 1/20 0.31
ADRB3 P13945 2/20 0.30
ADRA2B P18089 2/20 0.30
DRD1 P21728 2/20 0.30
DRD5 P21918 2/20 0.30
ADRA1B P35368 2/20 0.30
P2RY14 Q15391 2/20 0.30
TMEM97 Q5BJF2 2/20 0.30
SIGMAR1 Q99720 2/20 0.30
RPS6KA3 P51812 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19703000 0.87 CYP3A4 (0.38) CYP3A4CYP2C9APPCYP2D6CYP2C19
SCHEMBL13615183 0.86 CYP3A4 (0.40) CYP3A4CYP2C9APPCYP2D6CYP2C19
SCHEMBL19175840 0.85 SLC18A3 (0.40) SLC18A3LRRK2P2RY14TMEM97HDAC2
SCHEMBL29760209 0.85 SLC18A3 (0.40) SLC18A3LRRK2P2RY14TMEM97HDAC2
SCHEMBL19702997 0.85 CYP3A4 (0.36) CYP3A4CYP2C9APPCYP2D6CYP2C19
SCHEMBL9311508 0.84 CYP3A4 (0.35) CYP3A4CYP2C9APPCYP2D6CYP2C19
SCHEMBL8382880 0.84 CYP3A4 (0.35) CYP3A4CYP2C9APPCYP2D6CYP2C19
SCHEMBL9311501 0.84 CYP3A4 (0.35) CYP3A4CYP2C9APPCYP2D6CYP2C19
SCHEMBL8381522 0.84 CYP3A4 (0.35) CYP3A4CYP2C9APPCYP2D6CYP2C19
SCHEMBL8381523 0.84 CYP3A4 (0.35) CYP3A4CYP2C9APPCYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10344211-B2 Liquid crystal composition and liquid crystal display element using same DIC CORPORATION (JP) 2019-07-09 US disclosed
US-20170355906-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC CORPORATION (JP) 2017-12-14 US disclosed
US-20170355906-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC CORPORATION (JP) 2017-12-14 US disclosed