SCHEMBL13615183

SCHEMBL13615183

C=CC1CCC(c2ccc(-c3ccc(-c4ccc(C)cc4)c(F)c3)cc2)CC1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.40
CYP2C9 P11712 2/20 0.40
APP P05067 2/20 0.40
CYP2D6 P10635 1/20 0.39
CYP2C19 P33261 1/20 0.39
PDE3B Q13370 1/20 0.37
PDE3A Q14432 1/20 0.37
L3MBTL1 Q9Y468 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
SLC18A3 Q16572 1/20 0.32
PTGS2 P35354 2/20 0.31
LRRK2 Q5S007 1/20 0.31
FASN P49327 1/20 0.31
ADRB3 P13945 2/20 0.31
ADRA2B P18089 2/20 0.31
DRD1 P21728 2/20 0.31
DRD5 P21918 2/20 0.31
ADRA1B P35368 2/20 0.31
P2RY14 Q15391 2/20 0.31
TMEM97 Q5BJF2 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13614962 0.89 CYP3A4 (0.37) CYP3A4CYP2C9APPCYP2D6CYP2C19
SCHEMBL13140806 0.88 NPC1 (0.41) CYP3A4CYP2C9APPCYP2D6CYP2C19
SCHEMBL19702996 0.86 CYP3A4 (0.38) CYP3A4CYP2C9APPCYP2D6CYP2C19
SCHEMBL19702995 0.86 CYP3A4 (0.40) CYP3A4CYP2C9APPCYP2D6CYP2C19
SCHEMBL10065877 0.84 CYP3A4 (0.37) CYP3A4CYP2C9APPCYP2D6CYP2C19
SCHEMBL19493506 0.84 CYP3A4 (0.43) CYP3A4CYP2C9APPCYP2D6CYP2C19
SCHEMBL802781 0.84 CYP3A4 (0.43) CYP3A4CYP2C9APPCYP2D6CYP2C19
SCHEMBL19844711 0.84 SLC6A3 (0.40) CYP3A4CYP2C9APP
SCHEMBL21741418 0.84 CYP3A4 (0.54) CYP3A4CYP2C9APPCYP2D6CYP2C19
SCHEMBL8728184 0.83 CYP3A4 (0.36) CYP3A4CYP2C9APPCYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10344211-B2 Liquid crystal composition and liquid crystal display element using same DIC CORPORATION (JP) 2019-07-09 US disclosed
US-20170355906-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC CORPORATION (JP) 2017-12-14 US disclosed
US-20170355906-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC CORPORATION (JP) 2017-12-14 US disclosed
EP-2116522-A1 PENTACYCLIC LIQUID CRYSTAL COMPOUND HAVING CF<SB>2</SB>O BONDING GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY Chisso Corporation (JP) 2009-11-11 EP disclosed