Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.37 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 2/20 | 0.36 |
| ▸ | CCR5 | P51681 | 2/20 | 0.36 |
| ▸ | CCR8 | P51685 | 2/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | GPR3 | P46089 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2633153 | 0.80 | CYP1A2 (0.53) | CYP1A2KDM4EPSMD14COPS5CCR1 | |
| SCHEMBL18848439 | 0.80 | NOS1 (0.38) | CYP1A2KDM4ENOS1PARP1GPR3 | |
| SCHEMBL30666632 | 0.80 | CYP1A2 (0.53) | CYP1A2KDM4EPSMD14COPS5CCR1 | |
| SCHEMBL5545382 | 0.77 | CYP1A2 (0.50) | CYP1A2KDM4EPSMD14COPS5CCR1 | |
| SCHEMBL21893491 | 0.77 | PDGFRB (0.51) | CYP1A2ACHEKDM4EPSMD14COPS5 | |
| SCHEMBL4764348 | 0.77 | KDM4E (0.55) | CYP1A2KDM4EPSMD14COPS5CCR1 | |
| SCHEMBL14405531 | 0.77 | CYP1A2 (0.50) | CYP1A2KDM4EPSMD14COPS5CCR1 | |
| SCHEMBL5215594 | 0.77 | KDM4E (0.53) | CYP1A2ACHEKDM4EPSMD14COPS5 | |
| SCHEMBL29923227 | 0.77 | CYP1A2 (0.50) | CYP1A2KDM4EPSMD14COPS5CCR1 | |
| SCHEMBL6425923 | 0.77 | CYP1A2 (0.50) | CYP1A2KDM4EPSMD14COPS5CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017214458-A2 | ANTI-CD98 ANTIBODIES AND ANTIBODY DRUG CONJUGATES | ABBVIE INC. (US) | 2017-12-14 | — | — | WO | disclosed |