Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.45 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.45 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.45 |
| ▸ | KAT6A | Q92794 | 4/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19707231 | 0.87 | TAS1R3 (0.47) | TAS1R3TAS1R1TAS1R2GPR139KAT6A | |
| SCHEMBL5672983 | 0.85 | GSK3B (0.51) | TAS1R3TAS1R1TAS1R2GPR139KAT6A | |
| SCHEMBL19707370 | 0.85 | TAS1R3 (0.46) | TAS1R3TAS1R1TAS1R2GPR139KAT6A | |
| SCHEMBL19707234 | 0.85 | TAS1R3 (0.46) | TAS1R3TAS1R1TAS1R2GPR139KAT6A | |
| SCHEMBL19707325 | 0.82 | HDAC8 (0.51) | TAS1R3TAS1R1TAS1R2GPR139KAT6A | |
| SCHEMBL14099677 | 0.79 | HDAC8 (0.56) | TAS1R3TAS1R1TAS1R2GPR139KAT6A | |
| SCHEMBL29072684 | 0.77 | KAT6A (0.51) | TAS1R3TAS1R1TAS1R2GPR139KAT6A | |
| SCHEMBL30117137 | 0.77 | KAT6A (0.51) | TAS1R3TAS1R1TAS1R2GPR139KAT6A | |
| SCHEMBL690501 | 0.76 | KAT6A (0.54) | TAS1R3TAS1R1TAS1R2GPR139KAT6A | |
| SCHEMBL29393449 | 0.76 | KAT6A (0.52) | TAS1R3TAS1R1TAS1R2GPR139KAT6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017214505-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2017-12-14 | — | — | WO | disclosed |