⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21545609 | 1.00 | GLI1 (0.41) | — | |
| SCHEMBL12437074 | 0.89 | GLI1 (0.36) | — | |
| SCHEMBL9128397 | 0.89 | GLI1 (0.36) | — | |
| SCHEMBL8181948 | 0.89 | GLI1 (0.36) | — | |
| SCHEMBL2950685 | 0.89 | LMNA (0.43) | — | |
| SCHEMBL24511671 | 0.89 | GLI1 (0.36) | — | |
| SCHEMBL13783333 | 0.89 | GLI1 (0.36) | — | |
| SCHEMBL2950683 | 0.89 | LMNA (0.43) | — | |
| SCHEMBL14492218 | 0.89 | GLI1 (0.36) | — | |
| SCHEMBL18869482 | 0.89 | GLI1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 259 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12208088-B2 | Spirocyclic 2,3-dihydro-7-azaindole compounds and uses thereof | GENENTECH, INC. (US) | 2025-01-28 | — | — | US | claimed |
| CN-110804016-A | Diaryl quinoline derivatives against mycobacterium tuberculosis | 福建省微生物研究所 | 2020-02-18 | — | — | CN | claimed |
| CN-104193645-B | Preparation method of chiral dimethyl cyclopropyl carboxamide | 上海应用技术学院 | 2017-02-01 | — | — | CN | claimed |
| EP-2504314-B1 | QUINAZOLINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2015-08-05 | — | — | EP | claimed |
| US-9090605-B2 | Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use | VITAE PHARMACEUTICALS, INC. (US) | 2015-07-28 | — | — | US | claimed |
| US-20150080363-A1 | SUBSTITUTED 5-,6- AND 7-MEMBERED HETEROCYCLES, MEDICAMENTS CONTAINING SUCH COMPOUNDS, AND THEIR USE | VITAE PHARMACEUTICALS, INC. | 2015-03-19 | — | — | US | claimed |
| US-8933072-B2 | Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use | VITAE PHARMACEUTICALS, INC. (US) | 2015-01-13 | — | — | US | claimed |
| CN-104193645-A | Preparation method of chiral dimethyl cyclopropyl carboxamide | SHANGHAI INST TECHNOLOGY | 2014-12-10 | — | — | CN | claimed |
| US-8906930-B2 | Quinazoline derivatives | MERCK PATENT GMBH (DE) | 2014-12-09 | — | — | US | claimed |
| WO-2014114964-A2 | IMPROVED PROCESS FOR THE PREPARATION OF PRASUGREL AND INTERMEDIATE THEREOF | EGIS PHARMACEUTICALS PUBLIC LIMITED COMPANY (HU) | 2014-07-31 | — | — | WO | claimed |
| WO-2011159760-A1 | SUBSTITUTED 5-,6- AND 7-MEMBERED HETEROCYCLES, MEDICAMENTS CONTAINING SUCH COMPOUNDS, AND THEIR USE | VITAE PHARMACEUTICALS, INC. (US) | 2011-12-22 | — | — | WO | claimed |
| WO-2011061609-A2 | PROCESSES FOR THE PREPARATION OF CILASTATIN | RANBAXY LABORATORIES LIMITED (IN) | 2011-05-26 | — | — | WO | claimed |
| WO-2011060873-A1 | QUINAZOLINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2011-05-26 | — | — | WO | claimed |
| US-20100137605-A1 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES | ALBANY MOLECULAR RESEARCH, INC. (US) | 2010-06-03 | — | — | US | claimed |
| EP-2074105-A1 | CYCLOPROPYL-PIPERAZINE COMPOUNDS AS CALCIUM CHANNEL BLOCKERS | Neuromed Pharmaceuticals, Ltd. (CA) | 2009-07-01 | — | — | EP | claimed |
| WO-2008043183-A1 | CYCLOPROPYL-PIPERAZINE COMPOUNDS AS CALCIUM CHANNEL BLOCKERS | NEUROMED PHARMACEUTICALS LTD. (CA) | 2008-04-17 | — | — | WO | claimed |
| EP-1505966-A4 | 1,1-DISUBSTITUTED CYCLOALKYL DERIVATIVES AS FACTOR XA INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2006-08-30 | — | — | EP | claimed |
| CN-1824795-A | Optical selective screening process for amidase | UNIV ZHEJIANG POLYTECHNIC (CN) | 2006-08-30 | — | — | CN | claimed |
| EP-1505966-A1 | 1,1-DISUBSTITUTED CYCLOALKYL DERIVATIVES AS FACTOR XA INHIBITORS | Bristol-Myers Squibb Company (US) | 2005-02-16 | — | — | EP | claimed |
| WO-2003099276-A1 | 1,1-DISUBSTITUTED CYCLOALKYL DERIVATIVES AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-12-04 | — | — | WO | claimed |