⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19700375 | 0.80 | — | — | |
| SCHEMBL19209218 | 0.79 | FFAR3 (0.33) | — | |
| SCHEMBL19255881 | 0.76 | FFAR3 (0.31) | — | |
| SCHEMBL19257936 | 0.73 | SLC6A9 (0.30) | — | |
| SCHEMBL15758249 | 0.73 | SLC6A9 (0.30) | — | |
| SCHEMBL19209345 | 0.68 | CYP1A2 (0.32) | — | |
| SCHEMBL20221547 | 0.67 | NPSR1 (0.34) | — | |
| SCHEMBL19257640 | 0.66 | POLB (0.32) | — | |
| SCHEMBL30962480 | 0.65 | SLC6A9 (0.31) | — | |
| SCHEMBL17483508 | 0.61 | SLC6A9 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019113175-A1 | HEPATITIS B ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. (US) | 2019-06-13 | — | — | WO | disclosed |
| US-20170355701-A1 | HEPATITIS B ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. | 2017-12-14 | — | — | US | disclosed |
| WO-2017214395-A1 | HEPATITIS B ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. (US) | 2017-12-14 | — | — | WO | disclosed |