SCHEMBL197110

SCHEMBL197110

COC(=O)c1cc(Br)c(C(=O)OC)cc1Br

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SOS1 Q07889 1/20 0.50
CA1 P00915 4/20 0.47
CA2 P00918 4/20 0.47
CA9 Q16790 4/20 0.47
CA12 O43570 3/20 0.47
CA7 P43166 3/20 0.47
CA14 Q9ULX7 3/20 0.47
LCK P06239 1/20 0.47
FYN P06241 1/20 0.47
PDK2 Q15119 1/20 0.47
PDK4 Q16654 1/20 0.47
KMT2A Q03164 1/20 0.46
KDM4E B2RXH2 4/20 0.45
LMNA P02545 2/20 0.45
TSHR P16473 1/20 0.45
NR4A2 P43354 1/20 0.44
GAA P10253 3/20 0.44
ALDH1A1 P00352 2/20 0.44
HSD17B10 Q99714 2/20 0.44
MAPT P10636 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL70159 0.93 CA1 (0.45) SOS1CA1CA2CA9CA12
SCHEMBL29633948 0.91 LCK (0.60) SOS1CA1CA2CA9CA12
SCHEMBL2319843 0.91 LCK (0.60) SOS1CA1CA2CA9CA12
SCHEMBL12279551 0.91 SOS1 (0.45) SOS1CA1CA2CA9CA12
SCHEMBL23051540 0.90 SOS1 (0.50) SOS1CA1CA2CA9CA12
SCHEMBL2538919 0.89 KMT2A (0.44) SOS1CA1CA2CA9CA12
SCHEMBL20036871 0.89 KMT2A (0.44) SOS1CA1CA2CA9CA12
SCHEMBL8380009 0.88 SOS1 (0.50) SOS1CA1CA2CA9CA12
SCHEMBL8378560 0.88 GAA (0.49) SOS1CA1CA2CA9CA12
SCHEMBL14349262 0.88 SOS1 (0.50) SOS1CA1CA2CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114956976-A Novel indenofluorene-6, 12-diketone derivative and synthetic method and application thereof 商丘师范学院 2022-08-30 CN claimed
CN-105367451-B Near-infrared absorbing organic small molecule semiconductor material and preparation method and use 兰州大学 2017-05-10 CN claimed
CN-105367451-A Near-infrared absorbing organic small molecule semiconductor material and preparation method and use UNIV LANZHOU 2016-03-02 CN claimed
EP-0713502-B1 NAPHTHALENEDICARBOXYLIC ACID CONTAINING POLYMER/HALOGEN COMPOUND COMPOSITIONS HAVING REDUCED FLUORESCENCE EASTMAN CHEM CO (US) 1999-04-07 EP claimed
US-5418318-A Packaging EASTMAN CHEMICAL COMPANY (US) 1995-05-23 US claimed
US-4001188-A Dimethyl 2,5-dibromoterephthalate esterification STANDARD OIL COMPANY (INDIANA) (US) 1977-01-04 US claimed
CN-114956976-B Indenofluorene-6, 12-dione derivative and synthetic method and application thereof 商丘师范学院 2024-10-15 CN disclosed
CN-114891026-B Pyran ring-based A-D-pi-A type small molecule receptor material and application thereof 常州大学 2024-01-23 CN disclosed
US-11772069-B2 Multifunctional porous materials for water purification and remediation UNIVERSITY OF SOUTH FLORIDA (US) 2023-10-03 US disclosed
US-11772069-B2 Multifunctional porous materials for water purification and remediation UNIVERSITY OF SOUTH FLORIDA (US) 2023-10-03 US disclosed
US-11772069-B2 Multifunctional porous materials for water purification and remediation UNIVERSITY OF SOUTH FLORIDA (US) 2023-10-03 US disclosed
US-11744150-B2 Synthesis of aza-acenes as novel n-type materials for organic electronics UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2023-08-29 US disclosed
CN-111836680-B Multifunctional porous material for water purification and treatment 南佛罗里达大学 2023-06-20 CN disclosed
EP-0042261-A2 Electrically activatable recording material and a method of recording an image using the material EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1981-12-23 EP disclosed
US-4028308-A Poly(cyclohexanedimethylene dibromoterephthalate) STANDARD OIL COMPANY (INDIANA) (US) 1977-06-07 US disclosed
US-4025491-A SELF-EXTINGUISHING STANDARD OIL COMPANY (INDIANA) (US) 1977-05-24 US disclosed
US-4024102-A Molding composition suitable for forming improved flame retardant three-dimensional shaped articles CELANESE CORPORATION (US) 1977-05-17 US disclosed
US-4001188-A Dimethyl 2,5-dibromoterephthalate esterification STANDARD OIL COMPANY (INDIANA) (US) 1977-01-04 US disclosed
US-4001188-A Dimethyl 2,5-dibromoterephthalate esterification STANDARD OIL COMPANY (INDIANA) (US) 1977-01-04 US disclosed
US-3966682-A SELF-EXTINGUISHIMG STANDARD OIL COMPANY (US) 1976-06-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11744150-B2 Synthesis of aza-acenes as novel n-type materials for organic electronics ACE2, ACE, AZI2 SOS1 2841/4885CA1 1403/4885CA2 2117/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.