SCHEMBL70159

SCHEMBL70159

COC(=O)c1cc(C(=O)OC)c(Br)cc1Br

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.45
CA2 P00918 4/20 0.45
CA9 Q16790 4/20 0.45
CA12 O43570 3/20 0.45
CA7 P43166 3/20 0.45
CA14 Q9ULX7 3/20 0.45
KMT2A Q03164 1/20 0.45
LCK P06239 1/20 0.45
FYN P06241 1/20 0.45
PDK2 Q15119 1/20 0.45
PDK4 Q16654 1/20 0.45
SOS1 Q07889 1/20 0.45
KDM4E B2RXH2 4/20 0.44
LMNA P02545 2/20 0.43
TSHR P16473 1/20 0.43
NR4A2 P43354 1/20 0.43
GAA P10253 3/20 0.42
ALDH1A1 P00352 2/20 0.42
HSD17B10 Q99714 2/20 0.42
MAPT P10636 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL197110 0.93 SOS1 (0.50) CA1CA2CA9CA12CA7
SCHEMBL20799886 0.92 LCK (0.58) CA1CA2CA9CA12CA7
SCHEMBL15196571 0.88 KMT2A (0.40) CA1CA2CA9CA12CA7
SCHEMBL31301254 0.86 GAA (0.49) CA1CA2CA9CA12CA7
SCHEMBL15133527 0.86 KDM4E (0.59) CA1CA2CA9KMT2ALCK
SCHEMBL12279551 0.85 SOS1 (0.45) CA1CA2CA9CA12CA7
SCHEMBL29633948 0.85 LCK (0.60) CA1CA2CA9CA12CA7
SCHEMBL17782390 0.85 CA1 (0.50) CA1CA2CA9CA12CA7
SCHEMBL18432612 0.85 KMT2A (0.46) CA1CA2CA9CA12CA7
SCHEMBL2319843 0.85 LCK (0.60) CA1CA2CA9CA12CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117447294-A Preparation method and application of polycyclic conjugated aromatic hydrocarbon molecule containing methylene 华东理工大学 2024-01-26 CN disclosed
US-20230329092-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-10-12 US disclosed
EP-3679024-B1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2022-11-02 EP disclosed
EP-3679024-B1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2022-11-02 EP disclosed
US-20200283386-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2020-09-10 US disclosed
WO-2019048443-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2019-03-14 WO disclosed
US-9017577-B2 Indacenodithiophene and indacenodiselenophene polymers and their use as organic semiconductors MERCK PATENT GMBH (DE) 2015-04-28 US disclosed
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110226999-A1 Indacenodithiophene and Indacenodiselenophene Polymers and their Use as Organic Semiconductors MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG 2011-09-22 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
WO-2010020329-A1 INDACENODITHIOPHENE AND INDACENODISELENOPHENE POLYMERS AND THEIR USE AS ORGANIC SEMICONDUCTORS MERCK PATENT GMBH, (DE) 2010-02-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 CA1 550/4885CA2 612/4885CA9 1228/4885
US-20230329092-A1 MATERIALS FOR ELECTRONIC DEVICES SOD1, GPX1, EFNA1 CA1 2987/4885CA2 4418/4885CA9 2249/4885
US-20200283386-A1 MATERIALS FOR ELECTRONIC DEVICES EFNA1, GPX1, SOD1 CA1 2185/4885CA2 4215/4885CA9 1789/4885
US-20110226999-A1 Indacenodithiophene and Indacenodiselenophene Polymers and their Use as Organic Semiconductors ICMT, TST, INMT CA1 4196/4885CA2 4743/4885CA9 4063/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.