Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4138147 | 0.88 | HSD17B10 (0.50) | HSD17B10KMT2ALMNARAB9AMEN1 | |
| Hydrochloric Acid SCHEMBL19148315 | 0.86 | HSD17B10 (0.48) | HSD17B10KMT2ALMNARAB9AMEN1 | |
| Trifluoroacetic Acid SCHEMBL28510185 | 0.79 | HSD17B10 (0.42) | HSD17B10KMT2AMEN1KDM4E | |
| Trifluoroacetic Acid SCHEMBL7344714 | 0.79 | GAA (0.47) | HSD17B10LMNAKDM4E | |
| Trifluoroacetic Acid SCHEMBL6284934 | 0.76 | HSD17B10 (0.74) | HSD17B10LMNAKDM4E | |
| Trifluoroacetic Acid SCHEMBL6897031 | 0.76 | SIGMAR1 (0.44) | HSD17B10 | |
| SCHEMBL19711907 | 0.74 | KMT2A (0.35) | KMT2ALMNA | |
| SCHEMBL29606285 | 0.73 | KMT2A (0.38) | KMT2ALMNARAB9AMEN1KDM4E | |
| Trifluoroacetic Acid SCHEMBL28513537 | 0.73 | HSD17B10 (0.40) | HSD17B10KDM4E | |
| Trifluoroacetic Acid SCHEMBL28507621 | 0.73 | PIK3CD (0.46) | HSD17B10KMT2ALMNAMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112279848-A | Pan-JAKs inhibitor and application thereof | 四川海思科制药有限公司 | 2021-01-29 | — | — | CN | disclosed |
| EP-3256483-A2 | C-3 NOVEL TRITERPENONE WITH C-28 REVERSE AMIDE DERIVATIVES AS HIV INHIBITORS | Hetero Labs Limited (IN) | 2017-12-20 | — | — | EP | disclosed |