Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 10/20 | 0.47 |
| ▸ | PI4KA | P42356 | 1/20 | 0.36 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.36 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 3/20 | 0.32 |
| ▸ | COPS5 | Q92905 | 3/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27798083 | 0.75 | EGFR (0.47) | EGFRPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL29618252 | 0.75 | EGFR (0.47) | EGFRPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL2007641 | 0.75 | EGFR (0.47) | EGFRPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL18810410 | 0.75 | EGFR (0.47) | EGFRPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL3820499 | 0.75 | EGFR (0.47) | EGFRPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL4036487 | 0.75 | EGFR (0.47) | EGFRPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL1502533 | 0.75 | EGFR (0.47) | EGFRPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL277181 | 0.75 | EGFR (0.47) | EGFRPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL1261572 | 0.75 | EGFR (0.47) | EGFRPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL277182 | 0.75 | EGFR (0.47) | EGFRPI4KAPI4K2BPI4K2API4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017215682-A1 | A POLYMERIC MATRIX FOR THE PREPARATION OF MEMBRANES AND A MEMBRANE MADE OF THE POLYMERIC MATRIX | Technická univerzita v Liberci (CZ) | 2017-12-21 | — | — | WO | claimed |
| WO-2017215682-A1 | A POLYMERIC MATRIX FOR THE PREPARATION OF MEMBRANES AND A MEMBRANE MADE OF THE POLYMERIC MATRIX | Technická univerzita v Liberci (CZ) | 2017-12-21 | — | — | WO | disclosed |