SCHEMBL277182

SCHEMBL277182

Oc1cccc2ncncc12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 2/20 0.47
KDM4E B2RXH2 2/20 0.42
MAPKAPK2 P49137 1/20 0.42
ACHE P22303 1/20 0.40
ERN1 O75460 1/20 0.38
MAPT P10636 2/20 0.37
CYP1A2 P05177 2/20 0.37
APP P05067 1/20 0.37
THRB P10828 1/20 0.37
HPGD P15428 1/20 0.37
ALOX15 P16050 1/20 0.37
TSHR P16473 1/20 0.37
CASP1 P29466 1/20 0.37
SNCA P37840 1/20 0.37
RECQL P46063 1/20 0.37
HSD17B10 Q99714 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
GAA P10253 2/20 0.36
ALDH1A1 P00352 1/20 0.36
RAB9A P51151 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27682250 0.83 EGFR (0.44) EGFRKDM4EACHEERN1MAPT
1-Naphthol SCHEMBL27616902 0.78 EGFR (0.67) EGFRKDM4EMAPKAPK2ACHEMAPT
SCHEMBL4036487 0.75 EGFR (0.47) EGFRKDM4EMAPTGAARAB9A
SCHEMBL2007641 0.75 EGFR (0.47) EGFRKDM4ETDP1ALDH1A1PI4KA
SCHEMBL29618252 0.75 EGFR (0.47) EGFRKDM4EMAPTCYP1A2HPGD
SCHEMBL1261572 0.75 EGFR (0.47) EGFRKDM4EMAPTCYP1A2HPGD
SCHEMBL19716355 0.75 EGFR (0.47) EGFRKDM4EPI4KAPI4K2BPI4K2A
SCHEMBL277181 0.75 EGFR (0.47) EGFRKDM4EPI4KAPI4K2BPI4K2A
SCHEMBL3820499 0.75 EGFR (0.47) EGFRMAPTCYP1A2TSHRALDH1A1
SCHEMBL1502533 0.75 EGFR (0.47) EGFRPI4KAPI4K2BPI4K2API4KB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 156 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9821067-B2 Lipopeptides for delivery of nucleic acids MARINA BIOTECH, INC. (US) 2017-11-21 US claimed
WO-2016154694-A1 N-ACYLHYDRAZONE COMPOUNDS INHIBITING HISTONE DESACETYLASE ENZYMES, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME, AND METHOD FOR PRODUCING SAME UNIVERSIDADE FEDERAL DO RIO DE JANEIRO-UFRJ (BR) 2016-10-06 WO claimed
US-9220785-B2 Lipopeptides for delivery of nucleic acids MARINA BIOTECH, INC. (US) 2015-12-29 US claimed
CN-104672311-A Lipopeptides for delivery of nucleic acids MARINA BIOTECH INC 2015-06-03 CN claimed
US-20130231382-A1 LIPOPEPTIDES FOR DELIVERY OF NUCLEIC ACIDS MARINA BIOTECH, INC. (US) 2013-09-05 US claimed
CN-101939027-A Lipopeptides for delivery of nucleic acids MDRNA INC 2011-01-05 CN claimed
US-20100240731-A1 LIPOPEPTIDES FOR DELIVERY OF NUCLEIC ACIDS MDRNA, INC. (US) 2010-09-23 US claimed
CN-101674853-A Amino acid lipids and uses thereof NASTECH PHARM CO 2010-03-17 CN claimed
US-20080317839-A1 AMINO ACID LIPIDS AND USES THEREOF NASTECH PHARMACEUTICAL COMPANY INC. (US) 2008-12-25 US claimed
EP-1282680-A1 COMPOSITIONS COMPRISING CYCLODEXTRIN THE PROCTER & GAMBLE COMPANY (US) 2003-02-12 EP claimed
US-6503413-B2 Polyalkylene polysiloxane, buffering agent, aqueous carrier THE PROCTER & GAMBLE COMPANY 2003-01-07 US claimed
EP-1255806-A1 STABLE, AQUEOUS COMPOSITIONS FOR TREATING SURFACES, ESPECIALLY FABRICS THE PROCTER & GAMBLE COMPANY (US) 2002-11-13 EP claimed
US-20020011584-A1 Stable, aqueous compositions for treating surfaces, especially fabrics THE PROCTOR & GAMBLE COMPANY 2002-01-31 US claimed
US-20020010154-A1 Compositions comprising cyclodextrin THE PROCTER & GAMBLE COMPANY 2002-01-24 US claimed
WO-2001088076-A1 COMPOSITIONS COMPRISING CYCLODEXTRIN THE PROCTER & GAMBLE COMPANY (US) 2001-11-22 WO claimed
US-6289286-B1 Surface regeneration of biosensors and characterization of biomolecules associated therewith BIACORE AB (SE) 2001-09-11 US claimed
WO-2001060961-A1 STABLE, AQUEOUS COMPOSITIONS FOR TREATING SURFACES, ESPECIALLY FABRICS THE PROCTER & GAMBLE COMPANY (US) 2001-08-23 WO claimed
EP-1082607-A1 SURFACE REGENERATION OF BIOSENSORS Biacore AB (SE) 2001-03-14 EP claimed
WO-1999063333-A1 SURFACE REGENERATION OF BIOSENSORS BIACORE AB (SE) 1999-12-09 WO claimed
US-20260102395-A1 INHIBITING HISTONE DEACETYLASE 6 EIKONIZO THERAPEUTICS, INC. (US) 2026-04-16 US disclosed
US-12590084-B2 Oxadiazole HDAC6 inhibitors and uses thereof EIKONIZO THERAPEUTICS, INC. (US) 2026-03-31 US disclosed
US-20260055090-A1 OXADIAZOLE HDAC6 INHIBITORS AND USES THEREOF EIKONIZO THERAPEUTICS, INC. (US) 2026-02-26 US disclosed
US-20250250263-A1 INHIBITING HISTONE DEACETYLASE 6 (HDAC6) EIKONIZO THERAPEUTICS, INC. (US) 2025-08-07 US disclosed
US-20250230166-A1 OXADIAZOLE HDAC6 INHIBITORS AND USES THEREOF EIKONIZO THERAPEUTICS, INC. (US) 2025-07-17 US disclosed
CN-119451678-A Inhibition of histone deacetylase 6 (HDAC 6) 艾科尼佐治疗股份有限公司 2025-02-14 CN disclosed
EP-4504191-A1 INHIBITING HISTONE DEACETYLASE 6 (HDAC6) Eikonizo Therapeutics, Inc. (US) 2025-02-12 EP disclosed
EP-4504190-A1 OXADIAZOLE HDAC6 INHIBITORS AND USES THEREOF Eikonizo Therapeutics, Inc. (US) 2025-02-12 EP disclosed
CN-119212707-A Oxadiazole HDAC6 inhibitors and uses thereof 艾科尼佐治疗股份有限公司 2024-12-27 CN disclosed
EP-3252172-B1 FAST HYBRIDIZATION FOR NEXT GENERATION SEQUENCING TARGET ENRICHMENT AGILENT TECHNOLOGIES INC (US) 2024-09-11 EP disclosed
WO-2023196605-A1 INHIBITING HISTONE DEACETYLASE 6 (HDAC6) EIKONIZO THERAPEUTICS, INC. (US) 2023-10-12 WO disclosed
US-20230322747-A1 OXADIAZOLE HDAC6 INHIBITORS AND USES THEREOF EIKONIZO THERAPEUTICS, INC. (US) 2023-10-12 US disclosed
WO-2023196601-A1 OXADIAZOLE HDAC6 INHIBITORS AND USES THEREOF EIKONIZO THERAPEUTICS, INC. (US) 2023-10-12 WO disclosed
US-20230322747-A1 OXADIAZOLE HDAC6 INHIBITORS AND USES THEREOF EIKONIZO THERAPEUTICS, INC. (US) 2023-10-12 US disclosed
US-20230322747-A1 OXADIAZOLE HDAC6 INHIBITORS AND USES THEREOF EIKONIZO THERAPEUTICS, INC. (US) 2023-10-12 US disclosed
WO-2023196605-A1 INHIBITING HISTONE DEACETYLASE 6 (HDAC6) EIKONIZO THERAPEUTICS, INC. (US) 2023-10-12 WO disclosed
WO-2023196601-A1 OXADIAZOLE HDAC6 INHIBITORS AND USES THEREOF EIKONIZO THERAPEUTICS, INC. (US) 2023-10-12 WO disclosed
CN-112939995-A Process for preparing dioxanoquinazoline derivatives 北京工业大学 2021-06-11 CN disclosed
CN-111217821-B Preparation method of series dioxane quinazoline derivatives 北京工业大学 2021-04-23 CN disclosed
CN-111217821-A Preparation method of series dioxane quinazoline derivatives 北京工业大学 2020-06-02 CN disclosed
CN-105051018-B Heterocyclic substituted 2-amino-quinazoline derivatives for the treatment of viral infections 爱尔兰詹森科学公司 2019-09-20 CN disclosed
EP-3456845-A1 FAST HYBRIDIZATION FOR NEXT GENERATION SEQUENCING TARGET ENRICHMENT Agilent Technologies, Inc. (US) 2019-03-20 EP disclosed
EP-3441480-A1 FAST HYBRIDIZATION FOR NEXT GENERATION SEQUENCING TARGET ENRICHMENT Agilent Technologies, Inc. (US) 2019-02-13 EP disclosed
US-10093962-B2 Fast hybridization for next generation sequencing target enrichment AGILENT TECHNOLOGIES, INC. (US) 2018-10-09 US disclosed
EP-3252172-A2 FAST HYBRIDIZATION FOR NEXT GENERATION SEQUENCING TARGET ENRICHMENT Agilent Technologies, Inc. (US) 2017-12-06 EP disclosed
US-9821067-B2 Lipopeptides for delivery of nucleic acids MARINA BIOTECH, INC. (US) 2017-11-21 US disclosed
US-9587268-B2 Fast hybridization for next generation sequencing target enrichment AGILENT TECHNOLOGIES INC. (US) 2017-03-07 US disclosed
WO-2016154694-A1 N-ACYLHYDRAZONE COMPOUNDS INHIBITING HISTONE DESACETYLASE ENZYMES, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME, AND METHOD FOR PRODUCING SAME UNIVERSIDADE FEDERAL DO RIO DE JANEIRO-UFRJ (BR) 2016-10-06 WO disclosed
US-9339461-B2 Arginine-based lipids for delivery of therapeutics MARINA BIOTECH, INC. (US) 2016-05-17 US disclosed
US-20160058870-A1 LIPOPEPTIDES FOR DELIVERY OF NUCLEIC ACIDS MARINA BIOTECH INC (US) 2016-03-03 US disclosed
US-20160017405-A1 FAST HYBRIDIZATION FOR NEXT GENERATION SEQUENCING TARGET ENRICHMENT AGILENT TECHNOLOGIES, INC. (US) 2016-01-21 US disclosed
US-9220785-B2 Lipopeptides for delivery of nucleic acids MARINA BIOTECH, INC. (US) 2015-12-29 US disclosed
US-9115341-B2 Method for expanding hematopoietic stem cells using heterocyclic compound NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2015-08-25 US disclosed
EP-2902504-A1 Fast hybridization for next generation sequencing target enrichment Agilent Technologies, Inc. (US) 2015-08-05 EP disclosed
US-20150211047-A1 FAST HYBRIDIZATION FOR NEXT GENERATION SEQUENCING TARGET ENRICHMENT AGILENT TECHNOLOGIES, INC. (US) 2015-07-30 US disclosed
CN-104805180-A Fast hybridization for next generation sequencing target enrichment AGILENT TECHNOLOGIES INC 2015-07-29 CN disclosed
EP-1636192-B9 3-ALKYLIDENEHYDRAZINO SUBSTITUTED HETEROARYL COMPOUNDS AS THROMBOPOIETIN RECEPTOR ACTIVATORS NISSAN CHEMICAL IND LTD (JP) 2015-07-01 EP disclosed
CN-104382853-A Processes and Compositions for Liposomal and Efficient Delivery of Gene Silencing Therapeutics MARINA BIOTECH INC 2015-03-04 CN disclosed
US-8877729-B2 Amino acid lipids and uses thereof MARINA BIOTECH, INC. (US) 2014-11-04 US disclosed
CN-102231979-B Liposome efficient delivery methods and compositions for gene silencing therapeutics MARINA BIOTECH, INC. (US) 2014-10-29 CN disclosed
US-20140308304-A1 LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS ALNYLAM PHARMACEUTICALS, INC. 2014-10-16 US disclosed
US-20140051857-A1 HETEROCYCLIC COMPOUNDS AND THROMBOPOIETIN RECEPTOR ACTIVATORS NISSAN CHEMICAL INDUSTRIES LIMITED (JP) 2014-02-20 US disclosed
US-20140037714-A1 AMINO ACID LIPIDS AND USES THEREOF MARINA BIOTECH, INC. (US) 2014-02-06 US disclosed
EP-1636192-B1 3-ALKYLIDENEHYDRAZINO SUBSTITUTED HETEROARYL COMPOUNDS AS THROMBOPOIETIN RECEPTOR ACTIVATORS NISSAN CHEMICAL IND LTD (JP) 2014-01-15 EP disclosed
US-8552031-B2 3-ethylidenehydrazino substituted heterocyclic compounds as thrombopoietin receptor activators NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2013-10-08 US disclosed
US-8501824-B2 Amino acid lipids and uses thereof MARINA BIOTECH, INC. (US) 2013-08-06 US disclosed
WO-2013086373-A1 LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS ALNYLAM PHARMACEUTICALS, INC. (US) 2013-06-13 WO disclosed
US-8440666-B2 Pyridazinone compounds and P2X7 receptor inhibitors NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2013-05-14 US disclosed
CN-101674853-B Amino acid lipids and uses thereof NASTECH PHARM CO 2013-03-27 CN disclosed
US-20130039970-A1 Processes and Compositions for Liposomal and Efficient Delivery of Gene Silencing Therapeutics MARINA BIOTECH, INC. (US) 2013-02-14 US disclosed
US-20130012708-A1 HETEROCYCLIC COMPOUNDS AND THROMBOPOIETIN RECEPTOR ACTIVATORS NISSAN CHEMICAL INDUSTRIES LIMITED (JP) 2013-01-10 US disclosed
US-8318796-B2 Heterocyclic compounds and thrombopoietin receptor activators NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-11-27 US disclosed
US-8134013-B2 Amide compound and thrombopoietin receptor activator NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-03-13 US disclosed
US-8093251-B2 Nitrogen-containing heterocyclic compounds and thrombopoietin receptor activators NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-01-10 US disclosed
CN-102231979-A Liposome efficient delivery methods and compositions for gene silencing therapeutics MDRNA INC 2011-11-02 CN disclosed
US-8026368-B2 Hydrazide compounds and thrombopoietin receptor activators NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2011-09-27 US disclosed
US-20110177160-A1 Amino acid lipids and uses thereof MARINA BIOTECH, INC. (US) 2011-07-21 US disclosed
US-20110130327-A1 Multi-Arm Amines and Uses Thereof MARINA BIOTECH, INC. (US) 2011-06-02 US disclosed
US-7939505-B2 Amino acid lipids and uses thereof MARINA BIOTECH, INC. (US) 2011-05-10 US disclosed
US-20110077290-A1 HETEROCYCLIC COMPOUNDS AND THROMBOPOIETIN RECEPTOR ACTIVATORS NISSAN CHEMICAL INDUSTRIES LIMITED (JP) 2011-03-31 US disclosed
US-20100310537-A1 METHOD FOR EXPANDING HEMATOPOIETIC STEM CELLS USING HETEROCYCLIC COMPOUND NISSAN CHEMICAL INDUSTRIES LIMITED (JP) 2010-12-09 US disclosed
US-20100310536-A1 METHOD FOR EXPANDING HEMATOPOIETIC STEM CELLS USING HETEROCYCLIC COMPOUND NISSAN CHEMICAL INDUSTRIES LIMITED (JP) 2010-12-09 US disclosed
US-20100310535-A1 METHOD FOR EXPANDING HEMATOPOIETIC STEM CELLS USING HETEROCYCLIC COMPOUND NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2010-12-09 US disclosed
US-20100298559-A1 OPTICALLY ACTIVE DINICKEL COMPLEX AND METHOD FOR PRODUCING OPTICALLY ACTIVE AMINE USING THE OPTICALLY ACTIVE DINICKEL COMPLEX AS CATALYST NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2010-11-25 US disclosed
US-20100286390-A1 PYRIDAZINONE COMPOUNDS AND P2X7 RECEPTOR INHIBITORS NISSAN CHEMICAL INDUSTRIES LIMITED 2010-11-11 US disclosed
US-20100280042-A1 QUINAZOLINE DERIVATIVES FOR THE TREATMENT OF TUMOURS HENNEQUIN LAURENT FRANCOIS ANDRE 2010-11-04 US disclosed
EP-2233561-A1 METHOD FOR AMPLIFICATION OF HEMATOPOIETIC STEM CELL USING HETEROCYCLIC COMPOUND Nissan Chemical Industries, Ltd. (JP) 2010-09-29 EP disclosed
EP-2233468-A1 OPTICALLY ACTIVE DINICKEL COMPLEX AND METHOD FOR PRODUCING OPTICALLY ACTIVE AMINE USING THE OPTICALLY ACTIVE DINICKEL COMPLEX AS CATALYST Nissan Chemical Industries, Ltd. (JP) 2010-09-29 EP disclosed
EP-2228435-A1 METHOD FOR AMPLIFICATION OF HEMATOPOIETIC STEM CELL USING HETEROCYCLIC COMPOUND Nissan Chemical Industries, Ltd. (JP) 2010-09-15 EP disclosed
EP-2228434-A1 AMPLIFICATION METHOD FOR HEMATOPOIETIC STEM CELLS WITH HETEROCYCLIC COMPOUND Nissan Chemical Industries, Ltd. (JP) 2010-09-15 EP disclosed
EP-2203429-A1 PYRIDAZINONE DERIVATIVES AND USE THEREOF AS P2X7 RECEPTOR INHIBITORS Nissan Chemical Industries, Ltd. (JP) 2010-07-07 EP disclosed
US-20100112042-A1 Processes and Compositions for Liposomal and Efficient Delivery of Gene Silencing Therapeutics MDRNA, INC. (US) 2010-05-06 US disclosed
US-7696214-B2 Quinazoline derivatives for the treatment of tumours ASTRAZENECA AB (SE) 2010-04-13 US disclosed
CN-101674853-A Amino acid lipids and uses thereof NASTECH PHARM CO 2010-03-17 CN disclosed
US-7618777-B2 Composition and method for array hybridization AGILENT TECHNOLOGIES, INC. (US) 2009-11-17 US disclosed
US-20090281317-A1 3-ETHYLIDENEHYDRAZINO SUBSTITUTED HETEROCYCLIC COMPOUNDS AS THROMBOPOIETIN RECEPTOR ACTIVATORS NISSAN CHEMICAL INDUSTRIES LTD. (JP) 2009-11-12 US disclosed
US-20090253751-A1 HYDRAZIDE COMPOUND AND THROMBOPOIETIN RECEPTOR ACTIVATOR NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2009-10-08 US disclosed
US-7595415-B2 α-Substituted vinyltin compound NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2009-09-29 US disclosed
US-7576115-B2 Heterocyclic compounds and thrombopoietin receptor activators NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2009-08-18 US disclosed
US-20090198060-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND THROMBOPOIETIN RECEPTOR ACTIVATOR NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2009-08-06 US disclosed
US-20090131659-A1 AMIDE COMPOUND AND THROMBOPOIETIN RECEPTOR ACTIVATOR NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2009-05-21 US disclosed
WO-2009057827-A1 PYRIDAZINONE DERIVATIVES AND USE THEREOF AS P2X7 RECEPTOR INHIBITORS NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2009-05-07 WO disclosed
EP-2025671-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND THROMBOPOIETIN RECEPTOR ACTIVATOR Nissan Chemical Industries, Ltd. (JP) 2009-02-18 EP disclosed
US-20090023939-A1 ALPHA-SUBSTITUTED VINYLTIN COMPOUND NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2009-01-22 US disclosed
EP-1444211-B1 QUINAZOLINE DERIVATIVES AS ANTITUMOR AGENTS ASTRAZENECA AB (SE) 2009-01-21 EP disclosed
US-20080317839-A1 AMINO ACID LIPIDS AND USES THEREOF NASTECH PHARMACEUTICAL COMPANY INC. (US) 2008-12-25 US disclosed
US-20080207960-A1 Methods, compositions, and kits for post-hybridization processing of arrays AGILENT TECHNOLOGIES, INC. 2008-08-28 US disclosed
EP-1947101-A1 HYDRAZIDE COMPOUND AND THROMBOPOIETIN RECEPTOR ACTIVATOR Nissan Chemical Industries, Ltd. (JP) 2008-07-23 EP disclosed
US-7351841-B2 Heterocyclic compounds and thrombopoietin receptor activators NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2008-04-01 US disclosed
US-20080027068-A1 HETEROCYCLIC COMPOUNDS AND THROMBOPOIETIN RECEPTOR ACTIVATORS NISSAN CHEMICAL INDUSTRIES LIMITED (JP) 2008-01-31 US disclosed
CN-100345844-C Quinazoline derivatives for the treatment of tumours ASTRAZENECA AB (SE) 2007-10-31 CN disclosed
EP-1845090-A1 AMIDE COMPOUND AND THROMBOPOIETIN RECEPTOR ACTIVATOR Nissan Chemical Industries, Ltd. (JP) 2007-10-17 EP disclosed
CN-101035784-A New bicyclic antibiotics ACTELION PHARMACEUTICALS LTD (CH) 2007-09-12 CN disclosed
EP-1282680-B1 COMPOSITIONS COMPRISING CYCLODEXTRIN PROCTER & GAMBLE (US) 2007-09-05 EP disclosed
EP-1819692-A1 3-ETHYLIDENEHYDRAZINO SUBSTITUTED HETEROCYCLIC COMPOUNDS AS THROMBOPOIETIN RECEPTOR ACTIVATORS Nissan Chemical Industries, Ltd. (JP) 2007-08-22 EP disclosed
US-20070088044-A1 Quinazoline derivatives as antitumor agents ASTRAZENECA AB 2007-04-19 US disclosed
US-7160891-B2 Quinazoline derivatives for the treatment of T cell mediated diseases ASTRAZENECA AB (SE) 2007-01-09 US disclosed
US-20060258642-A1 Quinazoline derivatives for the treatment of tumours ASTRAZENECA AB 2006-11-16 US disclosed
EP-1255806-B1 STABLE, AQUEOUS COMPOSITIONS FOR TREATING SURFACES, ESPECIALLY FABRICS PROCTER & GAMBLE (US) 2006-09-27 EP disclosed
US-20060210997-A1 Composition and method for array hybridization AGILENT TECHNOLOGIES, INC. 2006-09-21 US disclosed
EP-1702990-A1 Composition and method for array hybridization Agilent Technologies, Inc. (US) 2006-09-20 EP disclosed
CN-1798739-A 3-alkylidenehydrazino substituted heteroaryl compounds as thrombopoietin receptor activators NISSAN CHEMICAL IND LTD (JP) 2006-07-05 CN disclosed
WO-2006062240-A1 3-ETHYLIDENEHYDRAZINO SUBSTITUTED HETEROCYCLIC COMPOUNDS AS THROMBOPOIETIN RECEPTOR ACTIVATORS NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2006-06-15 WO disclosed
US-7049438-B2 Quinazoline derivatives for treatment of tumours ASTRAZENECA AB (SE) 2006-05-23 US disclosed
US-20060094694-A1 Heterocyclic compounds and thrombopoietin receptor activators NISSAN CHEMICAL INDUSTRIES LIMITED (JP) 2006-05-04 US disclosed
CN-1764651-A Quinazoline derivatives as antitumor agents ASTRAZENECA AB (SE) 2006-04-26 CN disclosed
EP-1636192-A1 3-ALKYLIDENEHYDRAZINO SUBSTITUTED HETEROARYL COMPOUNDS AS THROMBOPOIETIN RECEPTOR ACTIVATORS Nissan Chemical Industries, Ltd. (JP) 2006-03-22 EP disclosed
EP-1450808-B8 QUINAZOLINE DERIVATIVES FOR THE TREATMENT OF T CELL MEDIATED DISEASES ASTRAZENECA AB (SE) 2006-01-04 EP disclosed
EP-1450808-B1 QUINAZOLINE DERIVATIVES FOR THE TREATMENT OF T CELL MEDIATED DISEASES ASTRAZENECA AB (SE) 2005-06-15 EP disclosed
US-20050054662-A1 Quinazoline derivatives as antitumor agents ASTRAZENECA AB (SE) 2005-03-10 US disclosed
US-20050038050-A1 Quinazoline derivatives for the treatment of t cell mediated diseases ASTRAZENECA AB (SE) 2005-02-17 US disclosed
WO-2004108683-A1 3-ALKYLIDENEHYDRAZINO SUBSTITUTED HETEROARYL COMPOUNDS AS THROMBOPOIETIN RECEPTOR ACTIVATORS NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2004-12-16 WO disclosed
US-20040214841-A1 Quinazoline derivatives for treatment of tumours ASTRAZENECA AB (SE) 2004-10-28 US disclosed
EP-1450808-A1 QUINAZOLINE DERIVATIVES FOR THE TREATMENT OF T CELL MEDIATED DISEASES Astrazeneca AB (SE) 2004-09-01 EP disclosed
EP-1292594-B1 QUINAZOLINE DERIVATIVES FOR THE TREATMENT OF TUMOURS ASTRAZENECA AB (SE) 2004-09-01 EP disclosed
EP-1444211-A2 QUINAZOLINE DERIVATIVES AS ANTITUMOR AGENTS AstraZeneca AB (SE) 2004-08-11 EP disclosed
CN-1434821-A Quinazoline derivatives for the treatment of tumours ASTRAZENECA AB (SE) 2003-08-06 CN disclosed
WO-2003045395-A1 QUINAZOLINE DERIVATIVES FOR THE TREATMENT OF T CELL MEDIATED DISEASES ASTRAZENECA AB (SE) 2003-06-05 WO disclosed
WO-2003040109-A2 QUINAZOLINE DERIVATIVES AS ANTITUMOR AGENTS ASTRAZENECA AB (SE) 2003-05-15 WO disclosed
WO-2001094341-A9 QUINAZOLINE DERIVATIVES FOR THE TREATMENT OF TUMOURS ASTRAZENECA AB (SE) 2003-04-17 WO disclosed
EP-1292594-A1 QUINAZOLINE DERIVATIVES FOR THE TREATMENT OF TUMOURS AstraZeneca AB (SE) 2003-03-19 EP disclosed
EP-1282680-A1 COMPOSITIONS COMPRISING CYCLODEXTRIN THE PROCTER & GAMBLE COMPANY (US) 2003-02-12 EP disclosed
US-6503413-B2 Polyalkylene polysiloxane, buffering agent, aqueous carrier THE PROCTER & GAMBLE COMPANY 2003-01-07 US disclosed
EP-1255806-A1 STABLE, AQUEOUS COMPOSITIONS FOR TREATING SURFACES, ESPECIALLY FABRICS THE PROCTER & GAMBLE COMPANY (US) 2002-11-13 EP disclosed
US-20020011584-A1 Stable, aqueous compositions for treating surfaces, especially fabrics THE PROCTOR & GAMBLE COMPANY 2002-01-31 US disclosed
US-20020010154-A1 Compositions comprising cyclodextrin THE PROCTER & GAMBLE COMPANY 2002-01-24 US disclosed
WO-2001094341-A1 QUINAZOLINE DERIVATIVES FOR THE TREATMENT OF TUMOURS ASTRAZENECA AB (SE) 2001-12-13 WO disclosed
WO-2001088076-A1 COMPOSITIONS COMPRISING CYCLODEXTRIN THE PROCTER & GAMBLE COMPANY (US) 2001-11-22 WO disclosed
US-6289286-B1 Surface regeneration of biosensors and characterization of biomolecules associated therewith BIACORE AB (SE) 2001-09-11 US disclosed
WO-2001060961-A1 STABLE, AQUEOUS COMPOSITIONS FOR TREATING SURFACES, ESPECIALLY FABRICS THE PROCTER & GAMBLE COMPANY (US) 2001-08-23 WO disclosed
EP-1082607-A1 SURFACE REGENERATION OF BIOSENSORS Biacore AB (SE) 2001-03-14 EP disclosed
WO-1999063333-A1 SURFACE REGENERATION OF BIOSENSORS BIACORE AB (SE) 1999-12-09 WO disclosed
US-5405843-A Anticancer drug potentiators MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1995-04-11 US disclosed
EP-0363212-B1 Novel heterocyclic compounds and anticancer-drug reinforcing agents containing them as effective components MITSUI TOATSU CHEMICALS (JP) 1995-01-04 EP disclosed
EP-0491814-A1 TETRACYCLIC IMIDAZOQUINAZOLINE DERIVATIVES, PREPARATION AND PHARMACEUTICAL COMPOSITIONS. NOVO NORDISK AS (DK) 1992-07-01 EP disclosed
US-5112817-A Anticancer Drug Potentiators MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1992-05-12 US disclosed
WO-1991003478-A1 TETRACYCLIC IMIDAZOQUINAZOLINE DERIVATIVES, PREPARATION AND PHARMACEUTICAL COMPOSITIONS NOVO NORDISK A/S (DK) 1991-03-21 WO disclosed
WO-1991003478-A1 TETRACYCLIC IMIDAZOQUINAZOLINE DERIVATIVES, PREPARATION AND PHARMACEUTICAL COMPOSITIONS NOVO NORDISK A/S (DK) 1991-03-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (40 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230322747-A1 OXADIAZOLE HDAC6 INHIBITORS AND USES THEREOF HDAC6, HDAC1, HDAC11 EGFR 3354/4885KDM4E 2674/4885MAPKAPK2 1161/4885
US-20130231382-A1 LIPOPEPTIDES FOR DELIVERY OF NUCLEIC ACIDS LNPEP, LPXN, SLC27A1 EGFR 1882/4885KDM4E 4784/4885MAPKAPK2 4127/4885
US-20110077290-A1 HETEROCYCLIC COMPOUNDS AND THROMBOPOIETIN RECEPTOR ACTIVATORS NR2C2, ROR1, NR0B2 EGFR 242/4885KDM4E 4480/4885MAPKAPK2 2152/4885
US-20060094694-A1 Heterocyclic compounds and thrombopoietin receptor activators NR2C2, ROR1, NR0B2 EGFR 213/4885KDM4E 4422/4885MAPKAPK2 2105/4885
US-20050054662-A1 Quinazoline derivatives as antitumor agents ERBB2, ERBB3, ABL1 EGFR 4/4885KDM4E 2435/4885MAPKAPK2 640/4885
US-20060210997-A1 Composition and method for array hybridization CDC73, DDHD2, TP53 EGFR 2073/4885KDM4E 4857/4885MAPKAPK2 3713/4885
US-20070088044-A1 Quinazoline derivatives as antitumor agents ERBB2, EGFR, ERBB4 EGFR 2/4885KDM4E 2238/4885MAPKAPK2 527/4885
US-20250230166-A1 OXADIAZOLE HDAC6 INHIBITORS AND USES THEREOF HDAC6, HDAC1, HDAC11 EGFR 3354/4885KDM4E 2674/4885MAPKAPK2 1161/4885
US-20080027068-A1 HETEROCYCLIC COMPOUNDS AND THROMBOPOIETIN RECEPTOR ACTIVATORS NR2C2, ROR1, NR0B2 EGFR 257/4885KDM4E 4486/4885MAPKAPK2 2213/4885
US-20080317839-A1 AMINO ACID LIPIDS AND USES THEREOF AADAT, AARS1, ABAT EGFR 234/4885KDM4E 3447/4885MAPKAPK2 3295/4885
US-20020010154-A1 Compositions comprising cyclodextrin FFAR4, FRG1, FGB EGFR 568/4885KDM4E 1253/4885MAPKAPK2 4222/4885
US-20060258642-A1 Quinazoline derivatives for the treatment of tumours TPD52L2, NQO2, H1-5 EGFR 1723/4885KDM4E 1901/4885MAPKAPK2 3906/4885
US-20100310535-A1 METHOD FOR EXPANDING HEMATOPOIETIC STEM CELLS USING HETEROCYCLIC COMPOUND HCLS1, CD44, NES EGFR 1087/4885KDM4E 2378/4885MAPKAPK2 4786/4885
US-12590084-B2 Oxadiazole HDAC6 inhibitors and uses thereof HDAC6, HDAC1, HDAC9 EGFR 1297/4885KDM4E 1491/4885MAPKAPK2 669/4885
US-20110130327-A1 Multi-Arm Amines and Uses Thereof SNRPE, SNRPA, ADAR EGFR 141/4885KDM4E 1453/4885MAPKAPK2 3578/4885
US-20100298559-A1 OPTICALLY ACTIVE DINICKEL COMPLEX AND METHOD FOR PRODUCING OPTICALLY ACTIVE AMINE USING THE OPTICALLY ACTIVE DINICKEL COMPLEX AS CATALYST C5, C9, CCNE1 EGFR 1909/4885KDM4E 2758/4885MAPKAPK2 2961/4885
US-20090131659-A1 AMIDE COMPOUND AND THROMBOPOIETIN RECEPTOR ACTIVATOR TEK, PTAFR, MPL EGFR 243/4885KDM4E 4435/4885MAPKAPK2 1568/4885
US-20160058870-A1 LIPOPEPTIDES FOR DELIVERY OF NUCLEIC ACIDS LNPEP, LPXN, SLC27A1 EGFR 1869/4885KDM4E 4812/4885MAPKAPK2 4034/4885
US-20260055090-A1 OXADIAZOLE HDAC6 INHIBITORS AND USES THEREOF HDAC6, HDAC1, CTTN EGFR 645/4885KDM4E 3413/4885MAPKAPK2 996/4885
US-20260102395-A1 INHIBITING HISTONE DEACETYLASE 6 HDAC6, HDAC1, HDAC8 EGFR 2282/4885KDM4E 866/4885MAPKAPK2 2770/4885
US-20100310536-A1 METHOD FOR EXPANDING HEMATOPOIETIC STEM CELLS USING HETEROCYCLIC COMPOUND HCLS1, CD44, NES EGFR 1247/4885KDM4E 2378/4885MAPKAPK2 4796/4885
US-20100240731-A1 LIPOPEPTIDES FOR DELIVERY OF NUCLEIC ACIDS LNPEP, LPXN, SLC27A1 EGFR 1882/4885KDM4E 4784/4885MAPKAPK2 4127/4885
US-20090198060-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND THROMBOPOIETIN RECEPTOR ACTIVATOR TEK, MPL, IL1RN EGFR 248/4885KDM4E 4616/4885MAPKAPK2 1982/4885
US-20140051857-A1 HETEROCYCLIC COMPOUNDS AND THROMBOPOIETIN RECEPTOR ACTIVATORS NR2C2, ROR1, NR0B2 EGFR 242/4885KDM4E 4480/4885MAPKAPK2 2152/4885
US-20100286390-A1 PYRIDAZINONE COMPOUNDS AND P2X7 RECEPTOR INHIBITORS P2RY1, P2RX7, P2RX1 EGFR 2861/4885KDM4E 3762/4885MAPKAPK2 603/4885
US-20100310537-A1 METHOD FOR EXPANDING HEMATOPOIETIC STEM CELLS USING HETEROCYCLIC COMPOUND HCLS1, CD44, NES EGFR 1247/4885KDM4E 2378/4885MAPKAPK2 4796/4885
US-20100112042-A1 Processes and Compositions for Liposomal and Efficient Delivery of Gene Silencing Therapeutics SLC27A2, LYPLA2, SLC47A2 EGFR 2068/4885KDM4E 4573/4885MAPKAPK2 1540/4885
US-20140308304-A1 LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS NPC1L1, NPC1, CETP EGFR 1466/4885KDM4E 3748/4885MAPKAPK2 3732/4885
US-20080207960-A1 Methods, compositions, and kits for post-hybridization processing of arrays PARG, PUF60, TP53 EGFR 2789/4885KDM4E 4204/4885MAPKAPK2 3890/4885
US-20130012708-A1 HETEROCYCLIC COMPOUNDS AND THROMBOPOIETIN RECEPTOR ACTIVATORS NR2C2, ROR1, NR0B2 EGFR 242/4885KDM4E 4480/4885MAPKAPK2 2152/4885
US-20090253751-A1 HYDRAZIDE COMPOUND AND THROMBOPOIETIN RECEPTOR ACTIVATOR TEK, THPO, PTAFR EGFR 649/4885KDM4E 4212/4885MAPKAPK2 1800/4885
US-20040214841-A1 Quinazoline derivatives for treatment of tumours NQO2, TOP1, TPD52L2 EGFR 1547/4885KDM4E 2520/4885MAPKAPK2 3573/4885
US-20130039970-A1 Processes and Compositions for Liposomal and Efficient Delivery of Gene Silencing Therapeutics SLC27A2, LYPLA2, SLC27A1 EGFR 2331/4885KDM4E 4127/4885MAPKAPK2 1549/4885
US-20140037714-A1 AMINO ACID LIPIDS AND USES THEREOF AADAT, AARS1, ABAT EGFR 234/4885KDM4E 3447/4885MAPKAPK2 3295/4885
US-20090023939-A1 ALPHA-SUBSTITUTED VINYLTIN COMPOUND TST, CCNT1, TMT1A EGFR 1817/4885KDM4E 1580/4885MAPKAPK2 4408/4885
US-20090281317-A1 3-ETHYLIDENEHYDRAZINO SUBSTITUTED HETEROCYCLIC COMPOUNDS AS THROMBOPOIETIN RECEPTOR ACTIVATORS MPL, TEK, THPO EGFR 200/4885KDM4E 4398/4885MAPKAPK2 1455/4885
US-20050038050-A1 Quinazoline derivatives for the treatment of t cell mediated diseases CD4, HLA-DRB1, IFNG EGFR 4734/4885KDM4E 1796/4885MAPKAPK2 3513/4885
US-20100280042-A1 QUINAZOLINE DERIVATIVES FOR THE TREATMENT OF TUMOURS TPD52L2, NQO2, H1-5 EGFR 1723/4885KDM4E 1901/4885MAPKAPK2 3906/4885
US-20250250263-A1 INHIBITING HISTONE DEACETYLASE 6 (HDAC6) HDAC6, HDAC1, HDAC9 EGFR 2951/4885KDM4E 1593/4885MAPKAPK2 954/4885
US-20110177160-A1 Amino acid lipids and uses thereof AADAT, AARS1, ABAT EGFR 234/4885KDM4E 3447/4885MAPKAPK2 3295/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.