Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 11/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10117715 | 1.00 | GAA (0.59) | GAASMN1; SMN2ALDH1A1LMNAPKM | |
| SCHEMBL13608334 | 0.86 | GAA (0.67) | GAASMN1; SMN2ALDH1A1LMNAPKM | |
| SCHEMBL13620311 | 0.85 | GAA (0.60) | GAASMN1; SMN2ALDH1A1LMNAPKM | |
| SCHEMBL1002985 | 0.84 | NPC1 (0.51) | SMN1; SMN2ALDH1A1LMNACYP3A4TSHR | |
| SCHEMBL10117690 | 0.83 | GAA (0.62) | GAASMN1; SMN2ALDH1A1LMNAPKM | |
| SCHEMBL13618767 | 0.81 | ALOX5 (0.50) | GAASMN1; SMN2ALDH1A1LMNAPKM | |
| SCHEMBL1134248 | 0.79 | GAA (0.39) | GAASMN1; SMN2ALDH1A1LMNAPKM | |
| SCHEMBL10117720 | 0.76 | GAA (0.56) | GAASMN1; SMN2ALDH1A1LMNAPKM | |
| SCHEMBL29220573 | 0.75 | PLAU (0.47) | GAAALDH1A1TSHRMAPT | |
| Phenylhydrazine SCHEMBL1134247 | 0.75 | CYP1A2 (0.44) | SMN1; SMN2ALDH1A1LMNAPKMCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2285773-B1 | CURE ACCELERATORS FOR ANAEROBIC CURABLE COMPOSITIONS | Henkel IP & Holding GmbH (DE) | 2017-12-20 | — | — | EP | disclosed |