Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR2 | P21802 | 5/20 | 0.31 |
| ▸ | CDK7 | P50613 | 2/20 | 0.31 |
| ▸ | CCNH | P51946 | 2/20 | 0.31 |
| ▸ | MNAT1 | P51948 | 2/20 | 0.31 |
| ▸ | CCNK | O75909 | 3/20 | 0.30 |
| ▸ | CDK12 | Q9NYV4 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19720782 | 0.88 | — | — | |
| SCHEMBL19720522 | 0.83 | — | — | |
| SCHEMBL19720551 | 0.83 | CYP1A2 (0.34) | — | |
| SCHEMBL16901704 | 0.81 | ALOX15 (0.34) | FGFR2CDK7CCNHMNAT1CCNK | |
| SCHEMBL19190242 | 0.81 | ALOX15 (0.34) | FGFR2CDK7CCNHMNAT1CCNK | |
| SCHEMBL16901705 | 0.81 | ALOX15 (0.34) | FGFR2CDK7CCNHMNAT1CCNK | |
| SCHEMBL23156772 | 0.80 | FGFR2 (0.34) | FGFR2CDK7CCNHMNAT1CCNK | |
| SCHEMBL22137956 | 0.80 | FGFR2 (0.34) | FGFR2CDK7CCNHMNAT1CCNK | |
| SCHEMBL20893424 | 0.80 | CCNK (0.35) | FGFR2CDK7CCNHMNAT1CCNK | |
| SCHEMBL22149110 | 0.80 | FGFR2 (0.34) | FGFR2CDK7CCNHMNAT1CCNK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3257848-A1 | COMPOUNDS AND COMPOSITIONS FOR MODULATING EGFR ACTIVITY | Novartis AG (CH) | 2017-12-20 | — | — | EP | disclosed |