Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | LIMK1 | P53667 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CLK1 | P49759 | 2/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | CHUK | O15111 | 1/20 | 0.35 |
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17528782 | 0.77 | GPR3 (0.40) | HPGDLMNARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL19721362 | 0.75 | HPGD (0.36) | HPGDLIMK1LMNANPC1TSHR | |
| SCHEMBL21253853 | 0.69 | — | — | |
| SCHEMBL21315919 | 0.69 | LIMK1 (0.35) | HPGDLIMK1LMNANPC1TSHR | |
| SCHEMBL26276459 | 0.69 | HPGD (0.34) | HPGDLIMK1LMNANPC1TSHR | |
| SCHEMBL24809807 | 0.67 | — | — | |
| SCHEMBL4903332 | 0.67 | LIMK1 (0.50) | HPGDLIMK1LMNANPC1TSHR | |
| SCHEMBL19255753 | 0.66 | KDM4E (0.37) | LMNANPC1ALDH1A1HSP90AA1MEN1 | |
| SCHEMBL24925925 | 0.65 | GPR3 (0.38) | HPGDLIMK1RAB9AIKBKBSMN1; SMN2 | |
| SCHEMBL23589522 | 0.65 | GPR3 (0.38) | RAB9AALDH1A1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3318566-B1 | AZADIBENZOFURANS FOR ELECTRONIC APPLICATIONS | UDC IRELAND LTD (IE) | 2020-06-24 | — | — | EP | disclosed |
| EP-3318566-A1 | AZADIBENZOFURANS FOR ELECTRONIC APPLICATIONS | UDC Ireland Limited (IE) | 2018-05-09 | — | — | EP | disclosed |
| EP-3063153-B1 | AZADIBENZOTHIOPHENES FOR ELECTRONIC APPLICATIONS | IDEMITSU KOSAN CO (JP) | 2018-03-07 | — | — | EP | disclosed |
| EP-2897959-B1 | AZADIBENZOFURANS FOR ELECTRONIC APPLICATIONS | UDC IRELAND LTD (IE) | 2017-12-20 | — | — | EP | disclosed |