⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL559559 | 0.79 | TAAR1 (0.56) | — | |
| SCHEMBL2030841 | 0.79 | TAAR1 (0.71) | — | |
| SCHEMBL11391510 | 0.74 | — | — | |
| SCHEMBL5805629 | 0.74 | — | — | |
| SCHEMBL1309954 | 0.74 | — | — | |
| SCHEMBL3674118 | 0.74 | — | — | |
| SCHEMBL20146704 | 0.74 | TAAR1 (0.73) | — | |
| SCHEMBL18071863 | 0.74 | — | — | |
| SCHEMBL677089 | 0.74 | — | — | |
| SCHEMBL8955423 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1989193-B1 | PROCESS FOR OBTAINING ENANTIOMERS OF DULOXETINE PRECURSORS | ESTEVE LABOR DR (ES) | 2011-06-22 | — | — | EP | disclosed |
| US-20090247771-A1 | PROCESS FOR OBTAINING ENANTIOMERS OF DULOXETINE PRECURSORS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2009-10-01 | — | — | US | disclosed |
| EP-1989193-A1 | PROCESS FOR OBTAINING ENANTIOMERS OF DULOXETINE PRECURSORS | Laboratorios Del. Dr. Esteve, S.A. (ES) | 2008-11-12 | — | — | EP | disclosed |
| WO-2007098923-A1 | PROCESS FOR OBTAINING ENANTIOMERS OF DULOXETINE PRECURSORS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2007-09-07 | — | — | WO | disclosed |
| EP-1828175-A2 | PROCESS FOR OBTAINING ENANTIOMERS OF THIENYLAZOLYLALCOXYETHANAMINES | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2007-09-05 | — | — | EP | disclosed |
| EP-1826204-A1 | Process for obtaining enantiomers of duloxetine precursors | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2007-08-29 | — | — | EP | disclosed |
| US-7078531-B2 | Process for obtaining enantiomers of thienylazolylalcoxyethanamines | LABORATORIES DEL DR. ESTEVE, S.A. (ES) | 2006-07-18 | — | — | US | disclosed |
| WO-2006063860-A2 | PROCESS FOR OBTAINING ENANTIOMERS OF THIENYLAZOLYLALCOXYETHANAMINES | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2006-06-22 | — | — | WO | disclosed |
| US-20060135787-A1 | PROCESS FOR OBTAINING ENANTIOMERS OF THIENYLAZOLYLALCOXYETHANAMINES | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2006-06-22 | — | — | US | disclosed |
| EP-1671968-A1 | Process for obtaining enantiomers of thienylazolylalcoxyethanamines | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2006-06-21 | — | — | EP | disclosed |