SCHEMBL677089

SCHEMBL677089

[NH]Cc1cccs1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1243429 0.79
SCHEMBL2030841 0.77 TAAR1 (0.71)
SCHEMBL559559 0.77 TAAR1 (0.56)
SCHEMBL5088326 0.76 TAAR1 (0.50)
SCHEMBL7338101 0.75
SCHEMBL1972145 0.74
SCHEMBL4656216 0.74
SCHEMBL2742130 0.74
SCHEMBL286875 0.74
SCHEMBL3674118 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 504 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114933598-B 6-Substituted harmine derivative, and preparation method and application thereof 乐山职业技术学院 2024-07-12 CN claimed
US-20240115553-A1 COMPOSITIONS AND METHODS FOR TREATING BRAIN INJURY AZEVAN PHARMACEUTICALS, INC. (US) 2024-04-11 US claimed
CN-113200967-B Indole benzoquinone compound, preparation method and application thereof 中国人民解放军陆军军医大学 2022-05-24 CN claimed
US-11319306-B2 Compositions and methods for treating neurodegenerative diseases AZEVAN PHARMACEUTICALS, INC. (US) 2022-05-03 US claimed
CN-112457363-B Potato trisaccharide oleanolic acid saponin derivative and preparation method and application thereof 华南农业大学 2021-12-24 CN claimed
CN-113200967-A Indole benzoquinone compound, preparation method and application thereof 中国人民解放军陆军军医大学 2021-08-03 CN claimed
CN-112457363-A Potato trisaccharide oleanolic acid saponin derivative and preparation method and application thereof 华南农业大学 2021-03-09 CN claimed
EP-3351104-B1 COMPOUNDS FOR USE IN THE TREATMENT OF INTERMITTENT EXPLOSIVE DISORDER AZEVAN PHARMACEUTICALS INC (US) 2020-12-09 EP claimed
EP-3002287-B1 Thiochromeno[2,3-c]quinolin-12-one derivatives and their use as topoisomerase inhibitors NAT DEFENSE MEDICAL CENTER (TW) 2018-01-31 EP claimed
US-9856216-B2 Compounds as TNIK, IKKε and TBK1 inhibitors and pharmaceutical composition comprising same GREEN CROSS CORPORATION (KR) 2018-01-02 US claimed
EP-0164944-B1 CEPHALOSPORIN DERIVATIVES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-07-11 EP claimed
EP-0210291-A1 Platinum complexes of antitumor agents AMERICAN CYANAMID COMPANY (US) 1987-02-04 EP claimed
EP-0117196-B1 DERIVATIVES OF N-IMINOPYRIDINIUM BETAINES, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS PROVESAN S.A. (CH) 1986-07-30 EP claimed
EP-0164944-A1 Cephalosporin derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-12-18 EP claimed
US-4507294-A TREATMENT OF PEPTIC ULCERS SCHERING CORP. (US) 1985-03-26 US claimed
EP-0117196-A1 Derivatives of N-iminopyridinium betaines, their preparation and their use as medicaments PROVESAN S.A. (CH) 1984-08-29 EP claimed
EP-0098951-A2 Aminobenzamide derivatives and preparation thereof STERLING DRUG INC. (US) 1984-01-25 EP claimed
US-4358454-A ANTIULCER AGENT SCHERING CORPORATION (US) 1982-11-09 US claimed
US-4358453-A ANTIULCER AGENTS SCHERING CORPORATION (US) 1982-11-09 US claimed
US-4312990-A HYPOTENSIVE AGENTS E. R. SQUIBB & SONS, INC. (US) 1982-01-26 US claimed