Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7876289 | 0.70 | — | — | |
| SCHEMBL28549077 | 0.70 | HCAR2 (0.35) | HCAR2KEAP1NFE2L2ALDH1A1HTT | |
| SCHEMBL4631733 | 0.68 | KDM4E (0.32) | HCAR2KEAP1NFE2L2MAPTKDM4E | |
| SCHEMBL4174002 | 0.68 | KDM4E (0.32) | HCAR2KEAP1NFE2L2MAPTKDM4E | |
| SCHEMBL4151495 | 0.68 | KDM4E (0.32) | HCAR2KEAP1NFE2L2MAPTKDM4E | |
| SCHEMBL28541989 | 0.66 | NFKB1 (0.33) | HCAR2KEAP1NFE2L2ALDH1A1GAA | |
| SCHEMBL28551156 | 0.65 | HCAR2 (0.36) | HCAR2KEAP1NFE2L2ALDH1A1HTT | |
| SCHEMBL20129480 | 0.65 | HCAR2 (0.62) | HCAR2KEAP1NFE2L2ALDH1A1HTT | |
| SCHEMBL20129404 | 0.65 | HCAR2 (0.62) | HCAR2KEAP1NFE2L2ALDH1A1HTT | |
| SCHEMBL20126398 | 0.65 | HCAR2 (0.62) | HCAR2KEAP1NFE2L2ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2847809-B1 | OLIGOMERIC ORGANIC LIGHT EMITTING DIODE(OLED)MATERIALS CONTAINING MULTIPLE CROSSLINKING FUNCTIONS | LOMOX LTD (GB) | 2017-12-20 | — | — | EP | disclosed |