Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18472817 | 0.98 | POLB (0.34) | HTTPOLBAPEX1TDP1 | |
| SCHEMBL18388199 | 0.95 | POLB (0.36) | HTTPOLBAPEX1TDP1TSHR | |
| SCHEMBL21034432 | 0.93 | POLB (0.35) | HTTPOLBAPEX1TDP1 | |
| SCHEMBL18522765 | 0.93 | POLB (0.35) | HTTPOLBAPEX1TDP1 | |
| SCHEMBL18473136 | 0.92 | POLB (0.34) | HTTPOLBAPEX1TDP1 | |
| SCHEMBL19722266 | 0.86 | POLB (0.32) | HTTPOLBAPEX1TDP1 | |
| SCHEMBL20614308 | 0.84 | — | — | |
| SCHEMBL21507736 | 0.82 | POLB (0.36) | HTTPOLBAPEX1TDP1TSHR | |
| SCHEMBL22003141 | 0.81 | POLB (0.37) | HTTPOLBAPEX1TDP1TSHR | |
| SCHEMBL18647054 | 0.78 | POLB (0.38) | HTTPOLBAPEX1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029127-B1 | LIQUID CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2017-12-20 | — | — | EP | disclosed |