Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18522765 | 1.00 | POLB (0.35) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL18388199 | 0.97 | POLB (0.36) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL18472817 | 0.95 | POLB (0.34) | POLBAPEX1HTTTDP1 | |
| SCHEMBL18473136 | 0.94 | POLB (0.34) | POLBAPEX1HTTTDP1 | |
| SCHEMBL19722266 | 0.93 | POLB (0.32) | POLBAPEX1HTTTDP1 | |
| SCHEMBL19721802 | 0.93 | HTT (0.35) | POLBAPEX1HTTTDP1 | |
| SCHEMBL20614308 | 0.86 | — | — | |
| SCHEMBL18647054 | 0.84 | POLB (0.38) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL21507736 | 0.84 | POLB (0.36) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL22003141 | 0.84 | POLB (0.37) | POLBAPEX1HTTTDP1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489329-A1 | LIQUID CRYSTALLINE MEDIUM | Merck Patent GmbH (DE) | 2019-05-29 | — | — | EP | disclosed |