SCHEMBL19721999

SCHEMBL19721999

CCCCCC1CCC(C2CCC(c3ccc(-c4ccc(OC)cc4)c(CC)c3)CC2)CC1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 2/20 0.37
FFAR4 Q5NUL3 1/20 0.34
CYP2C9 P11712 1/20 0.34
GRM2 Q14416 1/20 0.34
DGAT1 O75907 1/20 0.33
PPARG P37231 1/20 0.33
PPARD Q03181 1/20 0.33
PPARA Q07869 1/20 0.33
CNR1 P21554 3/20 0.33
CNR2 P34972 3/20 0.33
CASR P41180 1/20 0.33
CYP1A1 P04798 1/20 0.33
MAPT P10636 2/20 0.33
GAA P10253 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
GABRA1 P14867 1/20 0.32
GABRG2 P18507 1/20 0.32
GABRB3 P28472 1/20 0.32
GABRA3 P34903 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21321999 0.90 DRD2 (0.39) DRD2FFAR4CYP2C9DGAT1PPARG
SCHEMBL19722143 0.89 DRD2 (0.38) DRD2FFAR4CYP2C9GRM2DGAT1
SCHEMBL19721911 0.88 DRD2 (0.38) DRD2CYP2C9GRM2DGAT1MAPT
SCHEMBL21321907 0.85 CYP2C9 (0.47) FFAR4CYP2C9DGAT1MAPTGAA
SCHEMBL10766094 0.84 DRD2 (0.50) DRD2CYP2C9GRM2MAPTGAA
SCHEMBL10766092 0.84 DRD2 (0.50) DRD2CYP2C9GRM2MAPTGAA
SCHEMBL19755086 0.84 FFAR4 (0.34) FFAR4CYP2C9MAPTALDH1A1LMNA
SCHEMBL19722534 0.84 DRD2 (0.39) DRD2FFAR4CYP2C9GRM2DGAT1
SCHEMBL10383560 0.83 CYP2C9 (0.39) CYP2C9MAPTGAAALDH1A1LMNA
SCHEMBL10645734 0.83 CYP2C9 (0.39) CYP2C9MAPTGAAALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3257839-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT JNC Corporation (JP) 2017-12-20 EP disclosed