SCHEMBL19722613

SCHEMBL19722613

C=C(CN(CC)CC)C(=O)OC1CCC(c2ccc(CCCCC(F)(F)F)cc2)CC1

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ FFAR4 Q5NUL3 4/20 0.38
▸ SPHK1 Q9NYA1 13/20 0.37
▸ CACNA1G O43497 1/20 0.34
▸ CACNA1H O95180 1/20 0.34
▸ CACNA1I Q9P0X4 1/20 0.34
▸ SPHK2 Q9NRA0 7/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19755100 0.89 SPHK1 (0.48) FFAR4SPHK1SPHK2
SCHEMBL19721865 0.86 FFAR4 (0.40) FFAR4SPHK1
SCHEMBL19721923 0.77 FFAR4 (0.42) FFAR4
SCHEMBL19721964 0.76 SPHK1 (0.51) FFAR4SPHK1SPHK2
SCHEMBL19722091 0.75 SPHK1 (0.44) SPHK1SPHK2
SCHEMBL21298929 0.74 SPHK1 (0.46) FFAR4SPHK1SPHK2
SCHEMBL19721892 0.74 SPHK1 (0.48) FFAR4SPHK1SPHK2
SCHEMBL7790570 0.72 SPHK1 (0.52) SPHK1SPHK2
SCHEMBL7790568 0.72 SPHK1 (0.52) SPHK1SPHK2
SCHEMBL19721921 0.70 ESR2 (0.50) SPHK1SPHK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210214615-A1 LIQUID CRYSTAL DISPLAY DEVICE AND DISPLAY UNIT JNC CORPORATION (JP) 2021-07-15 — — US disclosed
EP-3257839-B1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2019-09-04 — — EP disclosed
US-10392339-B2 Polymerizable polar compound, liquid crystal composition, and liquid crystal display element JNC CORPORATION (JP) 2019-08-27 — — US disclosed
WO-2018025974-A1 LIQUID-CRYSTAL DISPLAY ELEMENT AND DISPLAY DEVICE JNC株式会社 2018-02-08 — — WO disclosed
EP-3257839-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT JNC Corporation (JP) 2017-12-20 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10392339-B2 Polymerizable polar compound, liquid crystal composition, and liquid crystal display element SP1, HVCN1, CXCR1 FFAR4 2665/4885SPHK1 435/4885CACNA1G 147/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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