Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 12/20 | 0.47 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.43 |
| ▸ | APP | P05067 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13975095 | 0.86 | KCNH2 (0.62) | KCNH2TLR8TLR7APPCYP2D6 | |
| SCHEMBL13975719 | 0.84 | KCNH2 (0.61) | KCNH2TLR8TLR7APPCYP2D6 | |
| SCHEMBL19723139 | 0.80 | KCNH2 (0.65) | KCNH2TLR8TLR7CYP2D6DRD1 | |
| SCHEMBL19723058 | 0.79 | EGFR (0.45) | KCNH2TLR8TLR7CYP2D6DRD1 | |
| SCHEMBL13975553 | 0.79 | EGFR (0.45) | KCNH2TLR8TLR7CYP2D6DRD1 | |
| SCHEMBL19723033 | 0.77 | KCNH2 (0.77) | KCNH2TLR8TLR7CYP2D6DRD1 | |
| SCHEMBL29945147 | 0.74 | CXCR2 (0.39) | KCNH2TLR8TLR7APPCYP2D6 | |
| SCHEMBL18109558 | 0.73 | TLR8 (0.67) | KCNH2TLR8TLR7 | |
| SCHEMBL19520036 | 0.73 | TLR8 (0.67) | KCNH2TLR8TLR7 | |
| SCHEMBL13975090 | 0.72 | CYP2D6 (0.62) | KCNH2TLR8TLR7CYP2D6ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2709989-B1 | QUINAZOLINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS AND FURTHER DISEASES | JANSSEN SCIENCES IRELAND UC (IE) | 2017-12-20 | — | — | EP | disclosed |