Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.36 |
| ▸ | GGPS1 | O95749 | 4/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28871041 | 0.79 | TLR8 (0.54) | TLR8TLR7KCNH2CYP2D6 | |
| SCHEMBL28871033 | 0.79 | TLR8 (0.43) | CXCR2TLR8TLR7KCNH2 | |
| SCHEMBL28871039 | 0.79 | TLR8 (0.54) | TLR8TLR7KCNH2CYP2D6 | |
| SCHEMBL28871092 | 0.79 | TLR8 (0.43) | CXCR2TLR8TLR7KCNH2 | |
| SCHEMBL28871032 | 0.77 | TLR8 (0.64) | TLR8TLR7KCNH2 | |
| SCHEMBL28871035 | 0.77 | TLR8 (0.64) | TLR8TLR7KCNH2 | |
| SCHEMBL13975095 | 0.74 | KCNH2 (0.62) | TLR8TLR7KCNH2APPCYP2D6 | |
| SCHEMBL19722984 | 0.74 | KCNH2 (0.47) | TLR8TLR7KCNH2APPCYP2D6 | |
| SCHEMBL13975090 | 0.74 | CYP2D6 (0.62) | TLR8TLR7KCNH2CYP2D6 | |
| SCHEMBL13975719 | 0.72 | KCNH2 (0.61) | TLR8TLR7KCNH2APPCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232146-A | 2-aminothieno [2,3-d ] pyrimidine compound and preparation method and application thereof | 山东大学 | 2022-10-25 | — | — | CN | disclosed |