Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 8/20 | 0.32 |
| ▸ | CA1 | P00915 | 8/20 | 0.32 |
| ▸ | CA2 | P00918 | 8/20 | 0.32 |
| ▸ | CA9 | Q16790 | 6/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14541036 | 0.85 | MEN1 (0.38) | MEN1GAAKMT2ASERPINE1SYK | |
| SCHEMBL14722015 | 0.84 | MEN1 (0.39) | MEN1GAAKMT2ASERPINE1SYK | |
| SCHEMBL19723141 | 0.84 | MEN1 (0.39) | MEN1GAAKMT2ASERPINE1SYK | |
| SCHEMBL569003 | 0.82 | SERPINE1 (0.43) | MEN1GAAKMT2ASERPINE1SYK | |
| SCHEMBL14726004 | 0.81 | TDP1 (0.43) | MEN1GAAKMT2ASERPINE1SYK | |
| SCHEMBL25189025 | 0.78 | SYK (0.43) | MEN1GAAKMT2ASERPINE1SYK | |
| SCHEMBL10029064 | 0.78 | SYK (0.43) | MEN1GAAKMT2ASERPINE1SYK | |
| SCHEMBL18361449 | 0.78 | SYK (0.43) | MEN1GAAKMT2ASERPINE1SYK | |
| SCHEMBL15876421 | 0.77 | SERPINE1 (0.40) | MEN1GAAKMT2ASERPINE1SYK | |
| SCHEMBL2860412 | 0.77 | MEN1 (0.42) | MEN1GAAKMT2ASERPINE1SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2748155-B1 | ISOXAZOLINE DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-12-20 | — | — | EP | disclosed |