Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 11/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14906424 | 1.00 | FPR2 (0.63) | FPR2RAB9APOLBMEN1KMT2A | |
| SCHEMBL14902658 | 1.00 | FPR2 (0.63) | FPR2RAB9APOLBMEN1KMT2A | |
| SCHEMBL29758787 | 0.96 | FPR2 (0.60) | FPR2RAB9APOLBMEN1KMT2A | |
| SCHEMBL14889945 | 0.85 | FPR2 (0.69) | FPR2RAB9APOLBMEN1KMT2A | |
| SCHEMBL14902579 | 0.85 | FPR2 (0.69) | FPR2RAB9APOLBMEN1KMT2A | |
| SCHEMBL19549550 | 0.85 | FPR2 (0.73) | FPR2RAB9APOLBMEN1KMT2A | |
| SCHEMBL14889583 | 0.85 | FPR2 (0.73) | FPR2RAB9APOLBMEN1KMT2A | |
| SCHEMBL14889988 | 0.85 | FPR2 (0.73) | FPR2RAB9APOLBMEN1KMT2A | |
| SCHEMBL19549513 | 0.85 | FPR2 (0.69) | FPR2RAB9APOLBMEN1KMT2A | |
| SCHEMBL14902659 | 0.85 | FPR2 (0.67) | FPR2RAB9APOLBLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9850264-B2 | Use of agonists of formyl peptide receptor 2 for treating ocular inflammatory diseases | ALLERGAN, INC. (US) | 2017-12-26 | — | — | US | claimed |
| EP-3078656-B1 | AMIDE DERIVATIVES OF N-UREA SUBSTITUTED AMINO ACIDS AS FORMYL PEPTIDE RECEPTOR LIKE-1 (FPRL-1) RECEPTOR MODULATORS | ALLERGAN INC (US) | 2020-07-01 | — | — | EP | disclosed |