Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19723734 | 0.92 | SMN1; SMN2 (0.59) | MAPTHTTPOLBNPC1RAB9A | |
| SCHEMBL19723544 | 0.91 | RAB9A (0.61) | MAPTHTTPOLBNPC1RAB9A | |
| SCHEMBL19723742 | 0.91 | MAPT (0.50) | MAPTHTTPOLBNPC1RAB9A | |
| SCHEMBL19723777 | 0.89 | MAPT (0.48) | MAPTHTTPOLBNPC1RAB9A | |
| SCHEMBL19723661 | 0.88 | MAPT (0.47) | MAPTHTTPOLBNPC1RAB9A | |
| SCHEMBL19723780 | 0.87 | SMN1; SMN2 (0.50) | MAPTHTTPOLBNPC1RAB9A | |
| SCHEMBL1768201 | 0.85 | RAB9A (0.69) | MAPTHTTPOLBNPC1RAB9A | |
| SCHEMBL19723651 | 0.85 | MAPT (0.55) | MAPTHTTPOLBNPC1RAB9A | |
| SCHEMBL19723647 | 0.84 | MAPT (0.53) | MAPTHTTPOLBNPC1RAB9A | |
| SCHEMBL19723550 | 0.84 | KMT2A (0.50) | MAPTHTTPOLBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3257854-A1 | IMIDAZO[1,2-A]PYRIDINE COMPOUNDS, SYNTHESIS THEREOF, AND METHODS OF USING SAME | University of Notre Dame du Lac (US) | 2017-12-20 | — | — | EP | disclosed |