Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | KDM4B | O94953 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 3/20 | 0.32 |
| ▸ | DRD2 | P14416 | 3/20 | 0.32 |
| ▸ | DRD4 | P21917 | 3/20 | 0.32 |
| ▸ | DRD3 | P35462 | 3/20 | 0.32 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19723948 | 0.98 | PDE2A (0.37) | PDE2AKDM4EHTTALDH1A1MEN1 | |
| SCHEMBL25231127 | 0.91 | KDM4E (0.41) | PDE2AKDM4EHTTALDH1A1MEN1 | |
| SCHEMBL7606761 | 0.83 | PLAT (0.41) | ALDH1A1MEN1KMT2APKM | |
| SCHEMBL17001808 | 0.83 | GAA (0.41) | PDE2AKDM4EHTTALDH1A1DRD2 | |
| SCHEMBL20485972 | 0.79 | AKT1 (0.35) | PDE2AALDH1A1MEN1KMT2APKM | |
| SCHEMBL14857892 | 0.77 | CYP2B6 (0.42) | KDM4EHTTMEN1KMT2ACHRM1 | |
| SCHEMBL20485938 | 0.77 | AKT1 (0.36) | PDE2AALDH1A1MEN1KMT2A | |
| SCHEMBL18192145 | 0.77 | ALDH1A1 (0.32) | PDE2AALDH1A1MEN1KMT2A | |
| SCHEMBL15464942 | 0.77 | ALDH1A1 (0.32) | PDE2AALDH1A1MEN1KMT2A | |
| SCHEMBL15465168 | 0.77 | ALDH1A1 (0.32) | PDE2AALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2974730-B1 | DRUG FOR RESPIRATORY DISEASES | DAIICHI SANKYO CO LTD (JP) | 2018-01-31 | — | — | EP | disclosed |
| EP-3144300-B1 | METHODS OF PRODUCING 4-CYCLOALKYLOXYBENZENESULFONAMIDES | DAIICHI SANKYO CO LTD (JP) | 2017-12-20 | — | — | EP | disclosed |