SCHEMBL197240

SCHEMBL197240

O=C(c1ccc(Oc2ccccc2)cc1)c1cc(Cl)ccc1Cl

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SERPINE1 P05121 1/20 0.58
SRD5A2 P31213 3/20 0.54
MAPT P10636 2/20 0.52
RAB9A P51151 1/20 0.52
KMT2A Q03164 2/20 0.51
ALDH1A1 P00352 2/20 0.50
TP53 P04637 1/20 0.50
POLB P06746 1/20 0.50
MEN1 O00255 1/20 0.50
GAA P10253 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
LMNA P02545 1/20 0.50
BCL2 P10415 2/20 0.49
MCL1 Q07820 2/20 0.49
NR4A1 P22736 1/20 0.49
STK39 Q9UEW8 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL596448 1.00 SERPINE1 (0.58) SERPINE1SRD5A2MAPTRAB9AKMT2A
SCHEMBL13371482 0.98 SRD5A2 (0.57) SERPINE1SRD5A2MAPTRAB9AKMT2A
SCHEMBL3675416 0.98 SRD5A2 (0.57) SERPINE1SRD5A2MAPTRAB9AKMT2A
SCHEMBL12360590 0.95 POLB (0.56) SERPINE1SRD5A2MAPTRAB9AKMT2A
SCHEMBL12122750 0.93 SERPINE1 (0.51) SERPINE1SRD5A2MAPTRAB9AKMT2A
SCHEMBL6517356 0.93 SERPINE1 (0.51) SERPINE1SRD5A2MAPTRAB9AKMT2A
SCHEMBL13321679 0.92 MAPT (0.56) SERPINE1SRD5A2MAPTRAB9AKMT2A
SCHEMBL13309945 0.92 SERPINE1 (0.51) SERPINE1SRD5A2MAPTRAB9AKMT2A
SCHEMBL13321681 0.91 MAPT (0.55) SERPINE1SRD5A2MAPTRAB9AKMT2A
SCHEMBL12122743 0.89 PARG (0.52) SERPINE1MAPTRAB9AKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9127129-B2 Star polymer ROBERT BOSCH GMBH (DE) 2015-09-08 US claimed
US-20120238699-A1 STAR POLYMER ROBERT BOSCH GMBH (DE) 2012-09-20 US claimed
EP-2456812-A1 STAR POLYMER Robert Bosch GmbH (DE) 2012-05-30 EP claimed
WO-2011009949-A1 STAR POLYMER ROBERT BOSCH GMBH (DE) 2011-01-27 WO claimed
US-5602228-A Nickel phosphate catalysts MAXDEM INCORPORATED (US) 1997-02-11 US claimed
WO-1996039455-A1 NICKEL PHOSPHITE CATALYSTS MAXDEM INCORPORATED (US) 1996-12-12 WO claimed
EP-2547383-B1 IMPROVED NEEDLES MADE OF A PARTICULAR PLASTIC MATERIAL SOLVAY SPECIALTY POLYMERS USA L L C (US) 2018-07-18 EP disclosed
US-20180057659-A1 THERMALLY STABILIZED POLYARYLENE COMPOSITIONS SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2018-03-01 US disclosed
EP-2925906-B1 METHOD FOR PREPARING A HIGH TEMPERATURE POLYMER COATING BAKER HUGHES INC (US) 2017-09-27 EP disclosed
US-9539361-B2 Prosthetic devices SOLVAY SPECIALTY POLYMERS USA, L.L.C. (US) 2017-01-10 US disclosed
EP-2328963-B1 POLYARYLENE COMPOSITIONS HAVING ENHANCED FLOW PROPERTIES SOLVAY SPECIALTY POLYMERS USA (US) 2016-04-06 EP disclosed
EP-2206547-B1 NITROGEN-CONTAINING AROMATIC COMPOUNDS AND PROCESSES FOR THE PRODUCTION OF THE SAME, POLYMERS AND PROTON CONDUCTIVE MEMBRANES OF THESE COMPOUNDS JSR CORP (JP) 2016-03-16 EP disclosed
EP-2328962-B1 THERMALLY STABILIZED POLYARYLENE COMPOSITIONS SOLVAY SPECIALTY POLYMERS USA (US) 2016-01-06 EP disclosed
EP-0629217-A4 RIGID-ROD POLYMERS. MAXDEM INC (US) 1995-03-29 EP disclosed
EP-0629217-A1 RIGID-ROD POLYMERS MAXDEM INCORPORATED (US) 1994-12-21 EP disclosed
WO-1994024717-A1 SULFONATED POLYMERS FOR SOLID POLYMER ELECTROLYTES MAXDEM INCORPORATED (US) 1994-10-27 WO disclosed
EP-0599886-A1 MACROMONOMERS HAVING REACTIVE END GROUPS MAXDEM INCORPORATED (US) 1994-06-08 EP disclosed
WO-1993018076-A1 RIGID-ROD POLYMERS MAXDEM INCORPORATED (US) 1993-09-16 WO disclosed
WO-1993018077-A1 RIGID-ROD POLYMERS MAXDEM INCORPORATED (US) 1993-09-16 WO disclosed
WO-1993004099-A1 MACROMONOMERS HAVING REACTIVE END GROUPS MAXDEM INCORPORATED (US) 1993-03-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120238699-A1 STAR POLYMER STARD3, STARD10, STARD7 SERPINE1 2260/4885SRD5A2 1235/4885MAPT 2803/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.