SCHEMBL6517356

SCHEMBL6517356

O=C(c1ccc(Oc2ccccc2Oc2ccccc2)cc1)c1cc(Cl)ccc1Cl

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SERPINE1 P05121 1/20 0.51
LMNA P02545 2/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
MAPT P10636 2/20 0.49
RAB9A P51151 1/20 0.49
KMT2A Q03164 2/20 0.48
ALDH1A1 P00352 2/20 0.47
MRGPRX4 Q96LA9 1/20 0.47
TP53 P04637 2/20 0.46
SRD5A2 P31213 2/20 0.46
P2RY1 P47900 1/20 0.45
NR4A1 P22736 1/20 0.45
PNLIP P16233 1/20 0.45
MEN1 O00255 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL596448 0.93 SERPINE1 (0.58) SERPINE1LMNAMAPTRAB9AKMT2A
SCHEMBL197240 0.93 SERPINE1 (0.58) SERPINE1LMNAMAPTRAB9AKMT2A
SCHEMBL13371482 0.92 SRD5A2 (0.57) SERPINE1LMNAMAPTRAB9AKMT2A
SCHEMBL3675416 0.92 SRD5A2 (0.57) SERPINE1LMNAMAPTRAB9AKMT2A
SCHEMBL12360590 0.89 POLB (0.56) SERPINE1LMNAMAPTRAB9AKMT2A
SCHEMBL12122750 0.86 SERPINE1 (0.51) SERPINE1LMNAMAPTRAB9AKMT2A
SCHEMBL13309945 0.85 SERPINE1 (0.51) SERPINE1LMNAMAPTRAB9AKMT2A
SCHEMBL13321679 0.85 MAPT (0.56) SERPINE1LMNAMAPTRAB9AKMT2A
SCHEMBL13321681 0.84 MAPT (0.55) SERPINE1MAPTRAB9AKMT2AALDH1A1
SCHEMBL6939259 0.83 PKM (0.54) LMNAL3MBTL1MAPTRAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1245554-B1 Monomer containing electron-withdrawing group and electron-donative group, and copolymer and proton-conductive membrane comprising same JSR CORP (JP) 2005-01-26 EP disclosed
US-6794480-B2 POLYARYLENE-BASED COPOLYMER USEFUL AS PROTON-CONDUCTIVE MEMBRANE WHICH CAN BE USED AS ELECTRON FOR PRIMARY BATTERY, ELECTROLYTE FOR SECONDARY BATTERY, HIGH MOLECULAR SOLID ELECTROLYTE FOR FUEL CELL JSR CORPORATION (JP) 2004-09-21 US disclosed
US-20020177656-A1 Monomer containing electron-withdrawing group and electron-donative group, and copolymer and proton-conductive membrane comprising same JSR CORPORATION (JP) 2002-11-28 US disclosed
EP-1245554-A1 Monomer containing electron-withdrawing group and electron-donative group, and copolymer and proton-conductive membrane comprising same JSR Corporation (JP) 2002-10-02 EP disclosed