Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 18/20 | 0.70 |
| ▸ | SSTR1 | P30872 | 3/20 | 0.51 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.39 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.39 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16252891 | 1.00 | SSTR4 (0.70) | SSTR4SSTR1PLK1HDAC1HDAC2 | |
| SCHEMBL19724420 | 0.93 | SSTR4 (0.70) | SSTR4SSTR1PLK1HDAC1HDAC2 | |
| SCHEMBL16252886 | 0.93 | SSTR4 (0.70) | SSTR4SSTR1PLK1HDAC1HDAC2 | |
| SCHEMBL16252874 | 0.87 | SSTR4 (0.68) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL19724403 | 0.87 | SSTR4 (0.68) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL17763141 | 0.83 | SSTR4 (0.65) | SSTR4SSTR1PLK1SSTR2SSTR3 | |
| SCHEMBL22015535 | 0.83 | SSTR4 (0.65) | SSTR4SSTR1PLK1SSTR2SSTR3 | |
| SCHEMBL19724364 | 0.82 | SSTR4 (1.00) | SSTR4SSTR1 | |
| SCHEMBL16252668 | 0.82 | SSTR4 (1.00) | SSTR4SSTR1 | |
| SCHEMBL19724468 | 0.82 | SSTR4 (1.00) | SSTR4SSTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2997021-B1 | NEW SOMATOSTATIN RECEPTOR SUBTYPE 4 (SSTR4) AGONISTS | CENTREXION THERAPEUTICS CORP (US) | 2017-12-20 | — | — | EP | disclosed |