Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 15/20 | 0.65 |
| ▸ | SSTR1 | P30872 | 4/20 | 0.48 |
| ▸ | SSTR2 | P30874 | 3/20 | 0.48 |
| ▸ | SSTR3 | P32745 | 3/20 | 0.48 |
| ▸ | SSTR5 | P35346 | 3/20 | 0.48 |
| ▸ | PLK1 | P53350 | 2/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17763141 | 1.00 | SSTR4 (0.65) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL17763130 | 0.88 | SSTR4 (0.64) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL17763077 | 0.83 | SSTR4 (0.65) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL16252891 | 0.83 | SSTR4 (0.70) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL19724366 | 0.83 | SSTR4 (0.70) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL17763209 | 0.83 | SSTR4 (0.65) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL17763140 | 0.83 | SSTR4 (0.65) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL17763086 | 0.81 | SSTR4 (0.66) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL17763220 | 0.80 | SSTR4 (0.64) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL17763143 | 0.80 | SSTR4 (0.66) | SSTR4SSTR1SSTR2SSTR3SSTR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3218372-B1 | MORPHOLINE AND 1,4-OXAZEPANE AMIDES AS SOMATOSTATIN RECEPTOR SUBTYPE 4 (SSTR4) AGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2020-05-20 | — | — | EP | disclosed |