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SCHEMBL19724971

SCHEMBL19724971

Cc1csc(C(C)(C)NC(=O)[C@H]2C3CNC[C@@H]32)n1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ SSTR4 P31391 20/20 1.00
▸ SSTR1 P30872 4/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16252613 1.00 SSTR4 (1.00) SSTR4SSTR1
SCHEMBL16252890 0.78 SSTR4 (0.64) SSTR4SSTR1
SCHEMBL19724398 0.78 SSTR4 (0.64) SSTR4SSTR1
SCHEMBL19724915 0.75 SSTR4 (1.00) SSTR4SSTR1
SCHEMBL17849521 0.75 SSTR4 (1.00) SSTR4SSTR1
SCHEMBL16252743 0.75 SSTR4 (1.00) SSTR4SSTR1
SCHEMBL19724858 0.75 SSTR4 (1.00) SSTR4SSTR1
SCHEMBL29676258 0.74 SSTR4 (0.58) SSTR4
SCHEMBL19724497 0.72 SSTR4 (1.00) SSTR4SSTR1
SCHEMBL16256034 0.72 SSTR4 (1.00) SSTR4SSTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2997021-B1 NEW SOMATOSTATIN RECEPTOR SUBTYPE 4 (SSTR4) AGONISTS CENTREXION THERAPEUTICS CORP (US) 2017-12-20 — — EP disclosed