Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 1/20 | 0.58 |
| ▸ | CNR2 | P34972 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25311505 | 0.81 | SSTR4 (0.41) | SSTR4CNR2MAPTRAB9ANPC1 | |
| SCHEMBL25307825 | 0.79 | SSTR4 (0.39) | SSTR4CNR2ALOX15 | |
| SCHEMBL19724475 | 0.76 | SSTR4 (0.47) | SSTR4CNR2MAPTRAB9ANPC1 | |
| SCHEMBL16366984 | 0.75 | SSTR4 (0.43) | SSTR4CNR2MAPTRAB9ANPC1 | |
| SCHEMBL16252613 | 0.74 | SSTR4 (1.00) | SSTR4 | |
| SCHEMBL19724971 | 0.74 | SSTR4 (1.00) | SSTR4 | |
| SCHEMBL634567 | 0.73 | SSTR4 (0.43) | SSTR4CNR2MAPTRAB9ANPC1 | |
| SCHEMBL132212 | 0.73 | SSTR4 (0.44) | SSTR4MAPTRAB9ANPC1PDE4A | |
| SCHEMBL12817180 | 0.72 | MAPK1 (0.56) | SSTR4CNR2RAB9ANPC1POLB | |
| SCHEMBL13151611 | 0.71 | SSTR4 (0.43) | SSTR4MAPTRAB9ANPC1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108617166-B | Protein kinase inhibitor benzolactam compounds | 大冢制药株式会社 | 2022-05-17 | — | — | CN | claimed |
| CN-114948963-B | Benzolactam compounds as protein kinase inhibitors | 大冢制药株式会社 | 2025-05-27 | — | — | CN | disclosed |
| CN-114948963-A | Protein kinase inhibitor benzolactam compounds | 大冢制药株式会社 | 2022-08-30 | — | — | CN | disclosed |
| CN-108617166-B | Protein kinase inhibitor benzolactam compounds | 大冢制药株式会社 | 2022-05-17 | — | — | CN | disclosed |