SCHEMBL197257

SCHEMBL197257

COc1cc2cccnc2c2ncccc12

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 5/20 0.61
CCR8 P51685 5/20 0.61
L3MBTL1 Q9Y468 4/20 0.56
PDGFRB P09619 1/20 0.56
PDGFRA P16234 1/20 0.56
DYRK1A Q13627 1/20 0.55
NSD2 O96028 1/20 0.50
CASP6 P55212 1/20 0.50
G6PD P11413 1/20 0.50
SLC40A1 Q9NP59 2/20 0.49
MAPT P10636 2/20 0.49
ALDH1A1 P00352 2/20 0.49
PDE10A Q9Y233 1/20 0.48
SYK P43405 1/20 0.47
HSP90AA1 P07900 2/20 0.47
NPC1 O15118 2/20 0.47
CCR5 P51681 3/20 0.47
LMNA P02545 3/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
KDM4E B2RXH2 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8119162 0.91 CCR1 (0.51) CCR1CCR8L3MBTL1PDGFRBPDGFRA
SCHEMBL13701006 0.84 CCR1 (0.58) CCR1CCR8L3MBTL1PDGFRBPDGFRA
SCHEMBL29193941 0.84 PDE10A (0.45) CCR1CCR8L3MBTL1PDGFRBPDGFRA
SCHEMBL30492645 0.81 CCR1 (0.62) CCR1CCR8L3MBTL1PDGFRBPDGFRA
SCHEMBL14069249 0.81 PDGFRB (0.54) CCR1CCR8PDGFRBPDGFRADYRK1A
SCHEMBL18806845 0.81 CCR1 (0.54) CCR1CCR8L3MBTL1PDGFRBPDGFRA
SCHEMBL10505657 0.81 CCR1 (0.62) CCR1CCR8L3MBTL1PDGFRBPDGFRA
SCHEMBL13596184 0.80 CCR1 (0.54) CCR1CCR8L3MBTL1DYRK1AMAPT
SCHEMBL8410414 0.79 SYK (0.59) PDGFRBPDGFRANSD2CASP6G6PD
SCHEMBL30062285 0.78 CCR1 (0.51) CCR1CCR8L3MBTL1PDGFRBPDGFRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230167144-A1 PREPARATION AND ITS APPLICATION OF A CYANIDE-BRIDGED METAL ORGANIC COMPOUND WITH INTRAMOLECULAR MAGNETIC TRANSFORMATION Hubei Jingmen Industrial Technology Research Institute Co., Ltd. (CN) 2023-06-01 US claimed
CN-111718381-A Osmium metal organic compound containing polypyridine ligand and preparation method and application thereof 荆楚理工学院 2020-09-29 CN claimed
CN-111518145-A Cyanide-bridged metal organic compound with intramolecular magnetic transformation, and preparation method and application thereof 荆楚理工学院 2020-08-11 CN claimed
EP-0546563-B1 Complex crystal TOYOTA MOTOR CO LTD (JP) 2000-11-08 EP claimed
US-5942616-A Metal ion coordinated complex crystal KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) 1999-08-24 US claimed
US-5646284-A AUTOMOBILE WINDSHIELDS THAT SCREEN LIGHT TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 1997-07-08 US claimed
EP-0546563-A2 Complex crystal TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 1993-06-16 EP claimed
CN-111518145-B Cyano-bridged metal organic compound with intramolecular magnetic transformation and preparation method and application thereof 荆楚理工学院 2023-06-20 CN disclosed
US-20230167144-A1 PREPARATION AND ITS APPLICATION OF A CYANIDE-BRIDGED METAL ORGANIC COMPOUND WITH INTRAMOLECULAR MAGNETIC TRANSFORMATION Hubei Jingmen Industrial Technology Research Institute Co., Ltd. (CN) 2023-06-01 US disclosed
CN-111718381-A Osmium metal organic compound containing polypyridine ligand and preparation method and application thereof 荆楚理工学院 2020-09-29 CN disclosed
CN-111518145-A Cyanide-bridged metal organic compound with intramolecular magnetic transformation, and preparation method and application thereof 荆楚理工学院 2020-08-11 CN disclosed
US-20180128767-A1 Small Volume In Vitro Analyte Sensor ABBOTT DIABETES CARE INC. (US) 2018-05-10 US disclosed
US-9891185-B2 Small volume in vitro analyte sensor ABBOTT DIABETES CARE INC. (US) 2018-02-13 US disclosed
CN-1322254-A Small volume in vitro analytical sensor containing diffusible or non-leachable redox mediator THERASENSE INC (US) 2001-11-14 CN disclosed
US-6299757-B1 ANALYTICAL SENSORS FOR THE DETECTION OF BIOANALYTES; ESPECIALLY MONITORING GLUCOSE LEVELS IN DIABETIC PATIENTS THERASENSE, INC. 2001-10-09 US disclosed
EP-0546563-B1 Complex crystal TOYOTA MOTOR CO LTD (JP) 2000-11-08 EP disclosed
US-5942616-A Metal ion coordinated complex crystal KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) 1999-08-24 US disclosed
US-5710273-A AND AN ANION OF TRIIODINE AND AN ACID, LIGHT ADJUSTING COMPONENT FOR AUTOMOBILE WINDSHIELDS TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 1998-01-20 US disclosed
US-5646284-A AUTOMOBILE WINDSHIELDS THAT SCREEN LIGHT TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 1997-07-08 US disclosed
EP-0546563-A2 Complex crystal TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 1993-06-16 EP disclosed