SCHEMBL13701006

SCHEMBL13701006

COc1cc2cc(C)cnc2c2ncccc12

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 5/20 0.58
CCR8 P51685 5/20 0.58
CCR5 P51681 3/20 0.58
PDGFRB P09619 1/20 0.44
PDGFRA P16234 1/20 0.44
NSD2 O96028 1/20 0.43
CASP6 P55212 1/20 0.43
G6PD P11413 1/20 0.43
SLC40A1 Q9NP59 1/20 0.43
L3MBTL1 Q9Y468 4/20 0.43
HSP90AA1 P07900 2/20 0.43
NPC1 O15118 2/20 0.43
DYRK1A Q13627 1/20 0.42
KDM4E B2RXH2 2/20 0.41
HTT P42858 2/20 0.41
MAPT P10636 2/20 0.41
MEN1 O00255 1/20 0.41
MAPK1 P28482 1/20 0.41
MMP14 P50281 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL197257 0.84 CCR1 (0.61) CCR1CCR8CCR5PDGFRBPDGFRA
SCHEMBL19961979 0.81 CCR1 (0.72) CCR1CCR8CCR5SLC40A1L3MBTL1
SCHEMBL8119162 0.77 CCR1 (0.51) CCR1CCR8CCR5PDGFRBPDGFRA
SCHEMBL30492679 0.74 CCR1 (1.00) CCR1CCR8CCR5SLC40A1L3MBTL1
SCHEMBL8756864 0.74 CCR1 (1.00) CCR1CCR8CCR5SLC40A1L3MBTL1
SCHEMBL12346094 0.73 CCR1 (0.56) CCR1CCR8CCR5L3MBTL1HSP90AA1
SCHEMBL11920833 0.73 L3MBTL1 (0.70) CCR1CCR8CCR5SLC40A1L3MBTL1
SCHEMBL23904743 0.72 CCR1 (0.52) CCR1CCR8CCR5PDGFRBPDGFRA
SCHEMBL12047592 0.71 CRHR1 (0.51) CCR1CCR8PDGFRBPDGFRANSD2
SCHEMBL8410414 0.71 SYK (0.59) PDGFRBPDGFRANSD2CASP6G6PD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090239982-A1 Ultraviolet Absorbent and Heterocyclic Compound FUJIFILM CORPORATION (JP) 2009-09-24 US disclosed
US-20090239982-A1 Ultraviolet Absorbent and Heterocyclic Compound FUJIFILM CORPORATION (JP) 2009-09-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090239982-A1 Ultraviolet Absorbent and Heterocyclic Compound CYP2A6, CYP2B6, XPO6 CCR1 1840/4885CCR8 2353/4885CCR5 2567/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.