Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.56 |
| ▸ | HTR2B | P41595 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | PARP1 | P09874 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.51 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30631752 | 0.85 | MAPT (0.55) | MAPTLMNAHTTKMT2AMEN1 | |
| SCHEMBL3441526 | 0.81 | HTT (0.54) | MAPTLMNAHTTKMT2AMEN1 | |
| Acetic Acid SCHEMBL5482846 | 0.80 | HTT (0.52) | MAPTLMNAHTTKMT2AMEN1 | |
| Ethenzamide SCHEMBL27612766 | 0.79 | MAPT (0.68) | MAPTLMNAHTTKMT2AMEN1 | |
| Ethenzamide SCHEMBL25624 | 0.79 | MAPT (0.68) | MAPTLMNAHTTKMT2AMEN1 | |
| SCHEMBL31208540 | 0.78 | SIRT3 (0.49) | KDM4E | |
| SCHEMBL27537822 | 0.78 | MAPT (0.62) | MAPTLMNAHTTKMT2AMEN1 | |
| SCHEMBL11547493 | 0.77 | KDM4E (0.66) | MAPTLMNAHTTKMT2AMEN1 | |
| Ethenzamide SCHEMBL22163775 | 0.77 | MAPT (0.66) | MAPTLMNAHTTKMT2AMEN1 | |
| Ethenzamide SCHEMBL4379591 | 0.77 | MAPT (0.66) | MAPTLMNAHTTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334646-A2 | SUBSTITUTED BENZAMIDES AS CANNABINOID RECEPTOR LIGANDS | Abbott Laboratories (US) | 2011-06-22 | — | — | EP | disclosed |
| WO-2010033543-A2 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2010-03-25 | — | — | WO | disclosed |