Ethenzamide

Ethenzamide

SCHEMBL25624

CCOc1ccccc1C(N)=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.68
MEN1 O00255 3/20 0.68
KMT2A Q03164 3/20 0.68
NR1I2 O75469 1/20 0.68
LMNA P02545 1/20 0.68
CHRM2 P08172 1/20 0.68
CYP3A4 P08684 1/20 0.68
ADRA2A P08913 1/20 0.68
OPRK1 P41145 1/20 0.68
HTR2B P41595 1/20 0.68
SLC6A3 Q01959 1/20 0.68
HDAC6 Q9UBN7 1/20 0.68
HTT P42858 1/20 0.63
HCRTR1 O43613 2/20 0.62
PARP1 P09874 3/20 0.58
KDM4E B2RXH2 1/20 0.58
IRAK4 Q9NWZ3 1/20 0.58
CTNNB1 P35222 1/20 0.55
GLA P06280 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethenzamide SCHEMBL27612766 1.00 MAPT (0.68) MAPTMEN1KMT2ANR1I2LMNA
Ethenzamide SCHEMBL22163775 0.98 MAPT (0.66) MAPTMEN1KMT2ANR1I2LMNA
Ethenzamide SCHEMBL5401172 0.98 MAPT (0.66) MAPTMEN1KMT2ANR1I2LMNA
Ethenzamide SCHEMBL4379591 0.98 MAPT (0.66) MAPTMEN1KMT2ANR1I2LMNA
Ethenzamide SCHEMBL5382992 0.93 MAPT (0.60) MAPTMEN1KMT2ANR1I2LMNA
SCHEMBL7932427 0.90 MEN1 (0.60) MAPTMEN1KMT2ANR1I2LMNA
Ethenzamide SCHEMBL14977210 0.89 HTT (0.60) MAPTMEN1KMT2ANR1I2LMNA
SCHEMBL1829556 0.86 LMNA (0.60) MAPTMEN1KMT2ANR1I2LMNA
SCHEMBL23041012 0.86 MAPT (0.53) MAPTMEN1KMT2ANR1I2LMNA
SCHEMBL3352936 0.85 LMNA (0.79) MAPTMEN1KMT2ANR1I2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6407 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12575248-B2 Zinc oxide nanomaterial and preparation method thereof and semiconductor device TCL TECHNOLOGY GROUP CORPORATION (CN) 2026-03-10 US claimed
US-20260000741-A1 METHOD OF AMELIORATING A PRO-INFLAMMATORY IMMUNOPHENOTYPE IN FARBER DISEASE SUBJECTS BY REPEATED ADMINISTRATION OF A RECOMBINANT HUMAN ACID CERAMIDASE ACERAGEN INC (US) 2026-01-01 US claimed
EP-4615506-A1 USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES Sahin, Fikret (TR) 2025-09-17 EP claimed
US-20250255781-A1 PROCESSES FOR PREPARATION OF 3-D PRINTED PHARMACEUTICAL PRODUCTS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-08-14 US claimed
US-12383515-B2 Compositions and methods of use of γ-ketoaldehyde scavengers for treating, preventing or improving nonalcoholic fatty liver disease (NAFLD), NASH, ALD or conditions related to the liver MTI BIOTECH, INC. (US) 2025-08-12 US claimed
US-12296043-B2 Liquisoft capsules PATHEON SOFTGELS INC. (US) 2025-05-13 US claimed
WO-2025062440-A1 TOPICAL NANO-DISPERSION COMPOSITIONS AND THEIR PREPARATION THEREOF PULSE PHARMACEUTICALS PVT. LTD (IN) 2025-03-27 WO claimed
US-12240852-B2 Co-crystals, method and apparatus for forming the same REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2025-03-04 US claimed
EP-4510999-A1 PROCESSES FOR PREPARATION OF 3-D PRINTED PHARMACEUTICAL PRODUCTS Bristol-Myers Squibb Company (US) 2025-02-26 EP claimed
EP-4167307-B1 ZINC OXIDE NANOMATERIAL AND PREPARATION METHOD THEREFOR, AND SEMICONDUCTOR DEVICE TCL TECH GROUP CORP (CN) 2025-02-05 EP claimed
US-4850716-A Remotely detectable sterilization monitor MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-07-25 US claimed
EP-0277741-A1 Spherical granules having core and their production Takeda Chemical Industries, Ltd. (JP) 1988-08-10 EP claimed
EP-0209403-A2 Process for preparing ultrafine particles of organic compounds Research Development Corporation of Japan (JP) 1987-01-21 EP claimed
US-4540602-A Process for the preparation of activated pharmaceutical compositions FREUND INDUSTRY COMPANY, LIMITED (JP) 1985-09-10 US claimed
EP-0078209-B1 PHARMACEUTICAL COMPOSITIONS WITH ANTALGIC EFFECT Laboratoires BOUCHARD (FR) 1985-02-06 EP claimed
US-4345470-A All plastic disposable thermometer AKZONA INCORPORATED (US) 1982-08-24 US claimed
US-4299727-A Disposable reversible thermometer AKZONA INCORPORATED (US) 1981-11-10 US claimed
US-4289088-A STEAM AUTOCLAVING, OXY AMIDES MINNESOTA MINING AND MANUFACTURING CO. (US) 1981-09-15 US claimed
US-4232552-A THERMOCHROMISM, DISPOSABLE THERMOMETERS AKZONA INCORPORATED (US) 1980-11-11 US claimed
US-3981683-A FOR USE IN AUTOCLAVE BIO-MEDICAL SCIENCES, INC. (US) 1976-09-21 US claimed