⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19715871 | 0.90 | PDE10A (0.33) | — | |
| SCHEMBL17949564 | 0.83 | — | — | |
| SCHEMBL17949386 | 0.79 | PDE10A (0.35) | — | |
| SCHEMBL17941520 | 0.79 | NPC1 (0.35) | — | |
| SCHEMBL17941539 | 0.79 | CNR2 (0.33) | — | |
| SCHEMBL17383194 | 0.76 | DDR1 (0.32) | — | |
| SCHEMBL17949520 | 0.76 | DDR1 (0.35) | — | |
| SCHEMBL30958295 | 0.75 | — | — | |
| SCHEMBL19755918 | 0.75 | — | — | |
| SCHEMBL19755914 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3247712-B1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2022-04-20 | — | — | EP | disclosed |
| US-20210332039-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-10-28 | — | — | US | disclosed |
| US-10981907-B2 | Pesticidally active polycyclic derivatives with sulfur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2021-04-20 | — | — | US | disclosed |
| US-20190144445-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-05-16 | — | — | US | disclosed |
| US-20170362224-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-12-21 | — | — | US | disclosed |
| US-20170362224-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-12-21 | — | — | US | disclosed |