Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19725903 | 0.90 | — | — | |
| SCHEMBL17949386 | 0.90 | PDE10A (0.35) | PDE10A | |
| SCHEMBL17949563 | 0.85 | PDE10A (0.34) | PDE10A | |
| SCHEMBL17941520 | 0.79 | NPC1 (0.35) | — | |
| SCHEMBL21020024 | 0.79 | DDR1 (0.33) | PDE10A | |
| SCHEMBL17941539 | 0.79 | CNR2 (0.33) | — | |
| SCHEMBL20465862 | 0.78 | PTGER4 (0.34) | — | |
| SCHEMBL21020026 | 0.77 | KCNH2 (0.33) | — | |
| SCHEMBL17949520 | 0.77 | DDR1 (0.35) | — | |
| SCHEMBL17895956 | 0.77 | POLB (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12134612-B2 | Pesticidally active polycyclic derivatives with sulfur containing substituents | SYNGENTA CROP PROTECTION AG (CH) | 2024-11-05 | — | — | US | disclosed |
| EP-3247712-B1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2022-04-20 | — | — | EP | disclosed |
| US-20210332039-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-10-28 | — | — | US | disclosed |
| US-20210332039-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-10-28 | — | — | US | disclosed |
| US-10981907-B2 | Pesticidally active polycyclic derivatives with sulfur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2021-04-20 | — | — | US | disclosed |
| US-10981907-B2 | Pesticidally active polycyclic derivatives with sulfur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2021-04-20 | — | — | US | disclosed |
| US-20190144445-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-05-16 | — | — | US | disclosed |
| US-10138238-B2 | Pesticidally active polycyclic derivatives with sulfur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2018-11-27 | — | — | US | disclosed |
| US-20170362224-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10981907-B2 | Pesticidally active polycyclic derivatives with sulfur containing substituents | DDT, ACHE, GSTM1 | PDE10A 1338/4885 |
| US-12134612-B2 | Pesticidally active polycyclic derivatives with sulfur containing substituents | DDT, ACHE, SQOR | PDE10A 1449/4885 |
| US-20190144445-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | DDT, ACHE, SQOR | PDE10A 1449/4885 |
| US-20170362224-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | DDT, SQOR, PTMS | PDE10A 1290/4885 |
| US-20210332039-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | DDT, ACHE, SQOR | PDE10A 1449/4885 |
| US-10138238-B2 | Pesticidally active polycyclic derivatives with sulfur containing substituents | DDT, SQOR, PTMS | PDE10A 1290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.