Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1968722 | 1.00 | IDH1 (0.49) | IDH1HSD11B1 | |
| SCHEMBL1968308 | 0.99 | IDH1 (0.48) | IDH1HSD11B1 | |
| SCHEMBL1969909 | 0.99 | IDH1 (0.48) | IDH1HSD11B1 | |
| SCHEMBL1968356 | 0.85 | HSD11B1 (0.56) | IDH1HSD11B1 | |
| SCHEMBL1971941 | 0.85 | HSD11B1 (0.56) | IDH1HSD11B1 | |
| SCHEMBL1969937 | 0.79 | IDH1 (0.60) | IDH1HSD11B1 | |
| SCHEMBL1970951 | 0.78 | IDH1 (0.59) | IDH1HSD11B1 | |
| SCHEMBL1970743 | 0.78 | IDH1 (0.59) | IDH1HSD11B1 | |
| SCHEMBL1970351 | 0.76 | HSD11B1 (0.61) | IDH1HSD11B1 | |
| SCHEMBL1973698 | 0.76 | IDH1 (0.58) | IDH1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2086939-B8 | PYRIDINE CARBOXAMIDES AS 11-BETA-HSD1 INHIBITORS | ASTRAZENECA AB (SE) | 2011-06-22 | — | — | EP | disclosed |
| EP-2086939-A2 | PYRIDINE CARBOXAMIDES AS 11-BETA-HSD1 INHIBITORS | AstraZeneca AB (SE) | 2009-08-12 | — | — | EP | disclosed |
| WO-2008053194-A2 | PYRIDINE CARBOXAMIDES AS 11-BETA-HSD1 INHIBITORS | ASTRAZENECA AB (SE) | 2008-05-08 | — | — | WO | disclosed |