SCHEMBL197278

SCHEMBL197278

CCOC(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.46
CA1 P00915 2/20 0.45
CA2 P00918 2/20 0.45
MAPT P10636 3/20 0.41
POLB P06746 2/20 0.41
KDM4E B2RXH2 2/20 0.41
KMT2A Q03164 2/20 0.41
NPSR1 Q6W5P4 1/20 0.38
HIF1A Q16665 1/20 0.37
ALDH1A1 P00352 3/20 0.37
PKM P14618 2/20 0.36
MEN1 O00255 1/20 0.36
LMNA P02545 1/20 0.36
HSD17B10 Q99714 1/20 0.36
TSHR P16473 1/20 0.36
CYP4F2 P78329 2/20 0.35
CYP4A11 Q02928 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2691524 1.00 THRB (0.46) THRBCA1CA2MAPTPOLB
SCHEMBL29114387 1.00 THRB (0.46) THRBCA1CA2MAPTPOLB
SCHEMBL5704769 1.00 THRB (0.46) THRBCA1CA2MAPTPOLB
SCHEMBL1233379 1.00 THRB (0.46) THRBCA1CA2MAPTPOLB
SCHEMBL3861059 1.00 THRB (0.46) THRBCA1CA2MAPTPOLB
SCHEMBL2691616 1.00 THRB (0.46) THRBCA1CA2MAPTPOLB
SCHEMBL5704701 1.00 THRB (0.46) THRBCA1CA2MAPTPOLB
SCHEMBL29017737 0.98 THRB (0.45) THRBCA1CA2MAPTPOLB
SCHEMBL29218022 0.98 THRB (0.45) THRBCA1CA2MAPTPOLB
SCHEMBL2050077 0.98 CA1 (0.43) THRBCA1CA2MAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 291 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080517-A Plastic base standard substance containing fluorine compound, and preparation method and application thereof 2026-05-26 CN claimed
CN-118931340-A Oil-resistant, corrosion-resistant and static-conducting polyurea coating as well as preparation method and application thereof 华南理工大学 2024-11-12 CN claimed
CN-117986494-A Viscosity reducing agent for thickened oil and application of viscosity reducing agent in thickened oil 德源生物科技(海南)集团有限公司 2024-05-07 CN claimed
CN-116607188-A Flexible copper ion selective electrode and preparation method thereof 重庆大学 2023-08-18 CN claimed
CN-114457586-B Preparation method of high-thermal-conductivity super-amphiphobic fabric with liquid drop one-way permeability 哈尔滨工业大学 2022-07-15 CN claimed
CN-114457586-A Preparation method of high-thermal-conductivity super-amphiphobic fabric with liquid drop one-way permeability 哈尔滨工业大学 2022-05-10 CN claimed
CN-110484228-B Thickened oil viscosity reducer, application thereof and thickened oil viscosity reducing method 中国石油化工股份有限公司 2022-04-12 CN claimed
CN-109336734-B Ethyl perfluorohexyl acetic acid and synthesis method thereof 苏州工业园区天意达新材料科技有限公司 2022-03-25 CN claimed
CN-113801645-A Thickened oil viscosity reducing agent, preparation method thereof and thickened oil viscosity reducing method 中国石油化工股份有限公司 2021-12-17 CN claimed
CN-108570850-B Preparation method of super-wetting woven fabric with excellent stability and tolerance for oil-water separation 湖北大学 2021-03-02 CN claimed
CN-104195539-A Reparation method for zinc super-hydrophobic surface UNIV CHINA PETROLEUM 2014-12-10 CN claimed
US-7598413-B2 Process for producing fluorine-containing alkylsulfonylaminoethyl α-substituted acrylate CENTRAL GLASS COMPANY, LIMITED (JP) 2009-10-06 US claimed
US-20090069595-A1 Process for Producing Fluorine-Containing Alkylsulfonylaminoethyl Alpha-Substituted Acrylate CENTRAL GLASS COMPANY, LIMITED (JP) 2009-03-12 US claimed
CN-1687180-A Method for preparing super branched polyacrylate fluorine and application in finishing agent for textile YINGZHENG SCIRNCE AND TECHNOLO (CN) 2005-10-26 CN claimed
US-20030194378-A1 Novel aerosol formulation containing a polar fluorinated molecule ASTRAZENECA AB (SE) 2003-10-16 US claimed
EP-1303258-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE AstraZeneca AB (SE) 2003-04-23 EP claimed
WO-2002003958-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE ASTRAZENECA AB (SE) 2002-01-17 WO claimed
US-4822860-A Fluorine-containing polymeric amine-amide compound and a method for the preparation thereof DIRECTOR GENERAL OF AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY (JP) 1989-04-18 US claimed
US-4189615-A RELFUXING PHILLIPS PETROLEUM COMPANY (US) 1980-02-19 US claimed
US-4156791-A Preparation of alcohols by treating esters with alkali metal borohydride PHILLIPS PETROLEUM COMPANY (US) 1979-05-29 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090069595-A1 Process for Producing Fluorine-Containing Alkylsulfonylaminoethyl Alpha-Substituted Acrylate AFF1, AFF2, AFF4 THRB 179/4885CA1 2527/4885CA2 2022/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.