Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 6/20 | 0.47 |
| ▸ | PIM1 | P11309 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 2/20 | 0.35 |
| ▸ | TOP2A | P11388 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19728714 | 0.91 | STAT3 (0.47) | TOP1PIM1KDM4EPOLBALDH1A1 | |
| SCHEMBL20912561 | 0.91 | TOP1 (0.48) | TOP1PIM1KDM4EPOLBALDH1A1 | |
| SCHEMBL20912565 | 0.90 | TOP1 (0.47) | TOP1PIM1KDM4EPOLBALDH1A1 | |
| SCHEMBL19728643 | 0.84 | STAT3 (0.54) | TOP1KDM4EPOLBALDH1A1HSP90AA1 | |
| SCHEMBL20912560 | 0.82 | STAT3 (0.48) | TOP1PIM1KDM4EPOLBALDH1A1 | |
| SCHEMBL20912629 | 0.81 | STAT3 (0.47) | TOP1KDM4EPOLBALDH1A1HSP90AA1 | |
| SCHEMBL19728743 | 0.81 | STAT3 (0.47) | TOP1KDM4EPOLBALDH1A1HSP90AA1 | |
| SCHEMBL19729059 | 0.77 | STAT3 (0.47) | TOP1PIM1KDM4EALDH1A1STAT3 | |
| SCHEMBL19729388 | 0.76 | ALDH1A1 (0.50) | PIM1KDM4EPOLBALDH1A1HSP90AA1 | |
| SCHEMBL7009332 | 0.76 | TOP1 (0.58) | TOP1PIM1KDM4EPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017217441-A1 | NOVEL PYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | 湧永製薬株式会社 | 2017-12-21 | — | — | WO | disclosed |