SCHEMBL1972992

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1976187	0.93	ESR1 (0.39)	ESR1TRPM8MAPK1KDM4ENPC1
	SCHEMBL1974809	0.89	EGFR (0.44)	ESR1MAPK1ALDH1A1LMNATSHR
	SCHEMBL1973361	0.85	CDC7 (0.39)	ESR1MAPK1MAPTLMNATSHR
	SCHEMBL1972250	0.84	ADORA2A (0.43)	ESR1MAPK1LMNATSHRCYP1A2
	SCHEMBL1974634	0.83	ESR1 (0.43)	ESR1MAPK1ALDH1A1MAPTLMNA
	SCHEMBL1974405	0.82	ESR1 (0.44)	ESR1MAPK1MAPTLMNATSHR
	SCHEMBL1973167	0.82	ESR1 (0.43)	ESR1MAPK1LMNATSHRCYP1A2
	SCHEMBL1974917	0.82	MAPT (0.44)	ESR1MAPK1KDM4EALDH1A1MAPT
	SCHEMBL1973776	0.82	EGFR (0.45)	ESR1MAPK1ALDH1A1LMNATSHR
	SCHEMBL1972674	0.80	L3MBTL1 (0.45)	ESR1MAPK1MAPTLMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.