Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | PREP | P48147 | 2/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 4/20 | 0.37 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.36 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14126349 | 0.85 | ALDH1A1 (0.38) | NPSR1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL25892904 | 0.81 | KDM4E (0.35) | NPSR1HPGDMEN1KMT2AMAOB | |
| SCHEMBL25315647 | 0.81 | PARP1 (0.33) | — | |
| SCHEMBL21729876 | 0.79 | SMN1; SMN2 (0.41) | KDM4EHSD17B10TSHR | |
| SCHEMBL30863908 | 0.79 | SMN1; SMN2 (0.41) | KDM4EHSD17B10TSHR | |
| SCHEMBL25891631 | 0.75 | SLC5A2 (0.38) | — | |
| SCHEMBL21729864 | 0.74 | — | — | |
| SCHEMBL20558746 | 0.73 | KDM4E (0.39) | HPGDKDM4EACHEALDH1A1HSD17B10 | |
| SCHEMBL25892869 | 0.73 | ALDH1A1 (0.39) | HPGDPREPKDM4EACHEALDH1A1 | |
| SCHEMBL20643215 | 0.73 | HTR2A (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10889574-B2 | Method for producing diphenylmethane derivative | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2021-01-12 | — | — | US | disclosed |
| US-10640496-B2 | Method for producing diphenylmethane derivative | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2020-05-05 | — | — | US | disclosed |
| US-20190169174-A1 | METHOD FOR PRODUCING DIPHENYLMETHANE DERIVATIVE | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2019-06-06 | — | — | US | disclosed |
| WO-2017217792-A1 | METHOD FOR PRODUCING DIPHENYLMETHANE DERIVATIVE | 주식회사 대웅제약 | 2017-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190169174-A1 | METHOD FOR PRODUCING DIPHENYLMETHANE DERIVATIVE | SLC5A2, SLC5A1, SLC2A1 | NPSR1 4331/4885HPGD 2644/4885MEN1 3985/4885 |
| US-10640496-B2 | Method for producing diphenylmethane derivative | SLC5A2, SLC5A1, SLC2A1 | NPSR1 4331/4885HPGD 2644/4885MEN1 3985/4885 |
| US-10889574-B2 | Method for producing diphenylmethane derivative | SLC5A2, SLC5A1, SLC2A1 | NPSR1 4331/4885HPGD 2644/4885MEN1 3985/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.