SCHEMBL197319

SCHEMBL197319

COC(=O)C(F)C(F)(F)F

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.40
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
ACHE P22303 1/20 0.35
CA14 Q9ULX7 2/20 0.34
ZDHHC7 Q9NXF8 1/20 0.33
CA12 O43570 1/20 0.32
KMT2A Q03164 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPK1 P28482 1/20 0.32
PKM P14618 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28912213 0.85 ALDH1A1 (0.33) SMN1; SMN2ALDH1A1
SCHEMBL28990219 0.82 TDP1 (0.38) SMN1; SMN2CA1CA2ACHEALDH1A1
SCHEMBL28371880 0.80 SMN1; SMN2 (0.37) SMN1; SMN2CA1CA2ACHECA14
SCHEMBL8651385 0.78 HTT (0.33) HTT
SCHEMBL12963060 0.77 CA1 (0.35) SMN1; SMN2CA1CA2ACHECA14
SCHEMBL3140450 0.76 SMN1; SMN2 (0.42) SMN1; SMN2CA1CA2ACHECA14
SCHEMBL2260945 0.76 HTT (0.32) HTT
SCHEMBL1241162 0.76 SMN1; SMN2 (0.42) SMN1; SMN2CA1CA2ACHECA14
SCHEMBL25288847 0.75 ALDH1A1 (0.41) ALDH1A1
SCHEMBL3868205 0.75 ALDH1A1 (0.42) KMT2AALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 413 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026102880-A1 FULL-TEMPERATURE-RANGE POLYMER-BASED SOLID ELECTROLYTE, SOLID-STATE BATTERY AND PREPARATION METHOD 固态离子能源科技(武汉)有限公司 2026-05-21 WO claimed
CN-119490607-A Full-temperature-range polymer-based solid electrolyte, solid battery and preparation method 固态离子能源科技(武汉)有限公司 2025-02-21 CN claimed
US-7598413-B2 Process for producing fluorine-containing alkylsulfonylaminoethyl α-substituted acrylate CENTRAL GLASS COMPANY, LIMITED (JP) 2009-10-06 US claimed
CN-100489520-C Analysis and determination method of tetrafluoro-propionic methyle ester methoxide DONGYUE SHENZHOU NEW MAT CO (CN) 2009-05-20 CN claimed
US-20090069595-A1 Process for Producing Fluorine-Containing Alkylsulfonylaminoethyl Alpha-Substituted Acrylate CENTRAL GLASS COMPANY, LIMITED (JP) 2009-03-12 US claimed
CN-101000328-A Analytical investigating method of tetrafluoro-propionic methyle ester methoxide DONGYUE SHENZHOU NEW MAT CO (CN) 2007-07-18 CN claimed
CN-1539827-A 6-substitution-5-fluorin-4-hydroxy miazines compound and intermediate, synthetic method and usage 中国科学院上海有机化学研究所 2004-10-27 CN claimed
CN-1455663-A Novel aerosol formulation containing polar fluorinated molecule ASTRAZENECA AB (SE) 2003-11-12 CN claimed
US-20030194378-A1 Novel aerosol formulation containing a polar fluorinated molecule ASTRAZENECA AB (SE) 2003-10-16 US claimed
EP-1303258-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE AstraZeneca AB (SE) 2003-04-23 EP claimed
WO-2002003958-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE ASTRAZENECA AB (SE) 2002-01-17 WO claimed
CN-1083466-A Synthesizing of desflurant ANAQUEST INC (US) 1994-03-09 CN claimed
JP-63211245-A None JP disclosed
JP-63303950-A None JP disclosed
WO-2026102880-A1 FULL-TEMPERATURE-RANGE POLYMER-BASED SOLID ELECTROLYTE, SOLID-STATE BATTERY AND PREPARATION METHOD 固态离子能源科技(武汉)有限公司 2026-05-21 WO disclosed
US-12620622-B2 Compound including sulfur-containing heterocyclic cation and bis(oxolato)borate anion, electrolytic solution and electrochemical device including the same DAIKIN INDUSTRIES, LTD. (JP) 2026-05-05 US disclosed
CN-1083466-A Synthesizing of desflurant ANAQUEST INC (US) 1994-03-09 CN disclosed
EP-0468681-A1 Alfa-fluorocarboxylic acid derivatives as intermediates for the preparation of fungicides ZENECA LIMITED (GB) 1992-01-29 EP disclosed
JP-S63303950-A FLUORINE-CONTAINING COMPOUND AND PRODUCTION THEREOF DAIKIN IND LTD 1988-12-12 JP disclosed
JP-S63211245-A PRODUCTION OF 2,3,3,3-TETRAFLUOROPROPENE DAIKIN IND LTD 1988-09-02 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12620622-B2 Compound including sulfur-containing heterocyclic cation and bis(oxolato)borate anion, electrolytic solution and electrochemical device including the same ASH2L, OLA1, ODC1 SMN1; SMN2 1758/4885CA1 167/4885CA2 32/4885
US-20090069595-A1 Process for Producing Fluorine-Containing Alkylsulfonylaminoethyl Alpha-Substituted Acrylate AFF1, AFF2, AFF4 SMN1; SMN2 1130/4885CA1 2527/4885CA2 2022/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.