Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 5/20 | 0.47 |
| ▸ | CXCL10 | P02778 | 1/20 | 0.45 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.45 |
| ▸ | CCL2 | P13500 | 1/20 | 0.45 |
| ▸ | CCL5 | P13501 | 1/20 | 0.45 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.45 |
| ▸ | SERPINC1 | P01008 | 1/20 | 0.43 |
| ▸ | FGF1 | P05230 | 2/20 | 0.37 |
| ▸ | BDNF | P23560 | 3/20 | 0.35 |
| ▸ | PTN | P21246 | 2/20 | 0.35 |
| ▸ | MDK | P21741 | 2/20 | 0.35 |
| ▸ | M6PR | P20645 | 1/20 | 0.33 |
| ▸ | FGF2 | P09038 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | IDUA | P35475 | 1/20 | 0.32 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.32 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14118445 | 1.00 | F10 (0.47) | F10CXCL10CXCL8CCL2CCL5 | |
| SCHEMBL15942927 | 0.91 | F10 (0.52) | F10CXCL10CXCL8CCL2CCL5 | |
| SCHEMBL10085262 | 0.91 | F10 (0.52) | F10CXCL10CXCL8CCL2CCL5 | |
| SCHEMBL15905314 | 0.81 | CXCL10 (0.40) | F10CXCL10CXCL8CCL2CCL5 | |
| SCHEMBL16728908 | 0.81 | CXCL10 (0.39) | F10CXCL10CXCL8CCL2CCL5 | |
| SCHEMBL782333 | 0.80 | CXCL10 (0.40) | F10CXCL10CXCL8CCL2CCL5 | |
| SCHEMBL28460941 | 0.80 | CXCL10 (0.40) | F10CXCL10CXCL8CCL2CCL5 | |
| SCHEMBL21840769 | 0.80 | CXCL10 (0.40) | F10CXCL10CXCL8CCL2CCL5 | |
| SCHEMBL22712706 | 0.80 | CXCL10 (0.40) | F10CXCL10CXCL8CCL2CCL5 | |
| SCHEMBL17847369 | 0.80 | CXCL10 (0.40) | F10CXCL10CXCL8CCL2CCL5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170362632-A1 | ENZYMATIC ACTIVITY ASSAYS FOR I2S | SHIRE HUMAN GENETIC THERAPIES, INC. | 2017-12-21 | — | — | US | disclosed |