SCHEMBL10085262

SCHEMBL10085262

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nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
F10 P00742 6/20 0.52
CXCL10 P02778 1/20 0.51
CXCL8 P10145 1/20 0.51
CCL2 P13500 1/20 0.51
CCL5 P13501 1/20 0.51
CXCL12 P48061 1/20 0.51
SERPINC1 P01008 2/20 0.47
HPSE Q9Y251 2/20 0.35
FGF1 P05230 2/20 0.34
M6PR P20645 1/20 0.33
BDNF P23560 2/20 0.32
PTN P21246 1/20 0.32
MDK P21741 1/20 0.32
LGALS8 O00214 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15942927 1.00 F10 (0.52) F10CXCL10CXCL8CCL2CCL5
SCHEMBL14118445 0.91 F10 (0.47) F10CXCL10CXCL8CCL2CCL5
SCHEMBL19731922 0.91 F10 (0.47) F10CXCL10CXCL8CCL2CCL5
SCHEMBL19527932 0.86 F10 (0.44) F10CXCL10CXCL8CCL2CCL5
SCHEMBL26715971 0.84 CXCL10 (0.43) F10CXCL10CXCL8CCL2CCL5
SCHEMBL15905314 0.81 CXCL10 (0.40) F10CXCL10CXCL8CCL2CCL5
SCHEMBL12304926 0.80 M6PR (0.41) F10CXCL10CXCL8CCL2CCL5
SCHEMBL15942923 0.80 M6PR (0.41) F10CXCL10CXCL8CCL2CCL5
SCHEMBL17484892 0.80 M6PR (0.41) F10CXCL10CXCL8CCL2CCL5
SCHEMBL17484873 0.80 M6PR (0.41) F10CXCL10CXCL8CCL2CCL5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8802156-B2 Pharmaceutical forms for the release of active compounds LABORATORIOS FARMACÉUTICOS ROVI, S.A. (ES) 2014-08-12 US disclosed
US-20120022020-A1 PHARMACEUTICAL FORMS FOR THE RELEASE OF ACTIVE COMPOUNDS LABORATORIOS FARMACEUTICOS ROVI S.A. (ES) 2012-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120022020-A1 PHARMACEUTICAL FORMS FOR THE RELEASE OF ACTIVE COMPOUNDS ALG1, HPSE, GAA F10 337/4885CXCL10 3293/4885CXCL8 2242/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.