Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 19/20 | 0.71 |
| ▸ | KIF23 | Q02241 | 1/20 | 0.53 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3496879 | 0.84 | KIF11 (0.70) | KIF11MAP1LC3BCYP3A4CYP2C19KCNH2 | |
| SCHEMBL4376437 | 0.79 | KIF11 (0.78) | KIF11KIF23MAP1LC3BCYP3A4CYP2C19 | |
| SCHEMBL4366741 | 0.79 | KIF11 (0.54) | KIF11KIF23MAP1LC3BCYP3A4CYP2C19 | |
| SCHEMBL3961772 | 0.77 | KIF11 (0.67) | KIF11KIF23MAP1LC3BCYP3A4CYP2C19 | |
| SCHEMBL3966803 | 0.77 | KIF11 (0.68) | KIF11KIF23MAP1LC3BCYP3A4CYP2C19 | |
| SCHEMBL3961738 | 0.77 | KIF11 (0.67) | KIF11KIF23MAP1LC3BCYP3A4CYP2C19 | |
| SCHEMBL5753789 | 0.77 | KIF11 (0.44) | KIF11KIF23MAP1LC3BCYP3A4CYP2C19 | |
| SCHEMBL5751482 | 0.75 | KIF11 (0.57) | KIF11KIF23MAP1LC3BCYP3A4CYP2C19 | |
| SCHEMBL4364319 | 0.75 | KIF11 (0.58) | KIF11KIF23MAP1LC3BCYP3A4CYP2C19 | |
| SCHEMBL360705 | 0.74 | KIF11 (0.68) | KIF11KIF23MAP1LC3BCYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017216791-A9 | ANTICANCER DRUG CONJUGATES | Ariel Scientific Innovations Ltd. (IL) | 2018-02-08 | — | — | WO | disclosed |
| WO-2017216791-A1 | ANTICANCER DRUG CONJUGATES | Ariel Scientific Innovations Ltd. (IL) | 2017-12-21 | — | — | WO | disclosed |