SCHEMBL19732533

SCHEMBL19732533

CCCCNCCCCCC(C)CC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.50
ALDH1A1 P00352 2/20 0.50
ADH1B P00325 3/20 0.39
ADH1C P00326 3/20 0.39
ADH1A P07327 3/20 0.39
ADH7 P40394 3/20 0.39
ADH4 P08319 2/20 0.39
S1PR2 O95136 5/20 0.38
S1PR4 O95977 5/20 0.38
S1PR1 P21453 5/20 0.38
S1PR3 Q99500 5/20 0.38
ACE2 Q9BYF1 1/20 0.38
S1PR5 Q9H228 1/20 0.38
CYP1A2 P05177 1/20 0.37
CYP2C19 P33261 1/20 0.37
EPHX1 P07099 3/20 0.37
CYP3A4 P08684 1/20 0.35
HRH4 Q9H3N8 1/20 0.35
HRH3 Q9Y5N1 1/20 0.35
OPRM1 P35372 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22421817 0.98 TSHR (0.52) TSHRALDH1A1ADH1BADH1CADH1A
SCHEMBL20626518 0.98 TSHR (0.52) TSHRALDH1A1ADH1BADH1CADH1A
SCHEMBL19261618 0.96 TSHR (0.56) TSHRALDH1A1ADH1BADH1CADH1A
SCHEMBL20880056 0.96 TSHR (0.56) TSHRALDH1A1ADH1BADH1CADH1A
SCHEMBL19670763 0.96 TSHR (0.56) TSHRALDH1A1ADH1BADH1CADH1A
SCHEMBL23879439 0.96 TSHR (0.56) TSHRALDH1A1ADH1BADH1CADH1A
SCHEMBL21385843 0.96 TSHR (0.56) TSHRALDH1A1ADH1BADH1CADH1A
SCHEMBL24086372 0.92 ALDH1A1 (0.52) TSHRALDH1A1ADH1BADH1CADH1A
SCHEMBL13005065 0.91 TSHR (0.44) TSHRALDH1A1ADH1BADH1CADH1A
SCHEMBL18531304 0.91 TSHR (0.56) TSHRALDH1A1ADH1BADH1CADH1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10434186-B2 Functionalized linear ligands and complexes thereof LUMIPHORE, INC. (US) 2019-10-08 US disclosed
US-20170360956-A1 FUNCTIONALIZED LINEAR LIGANDS AND COMPLEXES THEREOF LUMIPHORE, INC. 2017-12-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170360956-A1 FUNCTIONALIZED LINEAR LIGANDS AND COMPLEXES THEREOF CLTB, CLTA, EPCAM TSHR 804/4885ALDH1A1 1477/4885ADH1B 3191/4885
US-10434186-B2 Functionalized linear ligands and complexes thereof CLTB, CLTA, EPCAM TSHR 804/4885ALDH1A1 1477/4885ADH1B 3191/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.